Fact Sheet - Texas Tech University Health Sciences Center

Texas Tech MedCast Podcast Episode Fact Sheet
Podcast Series Reynolds Geriatrics Series • USMLE Step 1 Prep
Episode Title The Mysterious Streaking Follicle, Question 97
Personnel Joseph Bales, Carlos Contreras, Daniel George, Sakeena Jamaluddin, Tyler
Levick, Jose Lopez, Lindsey Nelson, Robert Obryan, Alicia Robinson, Allison
Strickland, Sudhir Thotakura
Recording Date April 20, 2010
USMLE Question
Number: 97
Pg #: 43
Learning
Objectives
The listener
should be able to:
Key Teaching
Points
Texas Tech MedCast Producer: Betsy Goebel Jones, Ed.D., betsy.jones@ttuhsc.edu
Prepared for the MS2 Aging Block at Texas Tech University Health Sciences Center School of
Medicine, Andrew Dentino, M.D., Block Director, andrew.dentino@ttuhsc.edu
http://www.ttuhsc.edu/som/fammed/ttmedcast/gerseries/gerstep1prep.aspx
Group 12
A 55-year-old woman has a hysterectomy and bilateral salpingooophorectomy
for abnormal uterine bleeding. Histologic examination of the
ovaries shows small atretic follicles. Which of the following processes is
the most likely cause of these histologic findings?
(A) Apoptosis
(B) Metamorphosis
(C) Metaplasia
(D) Necrosis
(E) Transformation
1. Understand the normal histological changes in a woman going through
menopause.
2. Know the causes of abnormal uterine bleeding.
3. Know and be able to differentiate between the kinds of changes cells
and tissues can undergo, including apoptosis, necrosis, and metaplasia.
• Apoptosis is a phenomenon that serves to eliminates cells that are no
longer needed (programmed cell death), and is a normal process that

Texas Tech MedCast Podcast Episode Fact Sheet
USMLE Test
source:
Keywords
References
occurs in the ovarian follicles of menopausal women due to the
withdrawal of estrogen.
• Metaplasia is the replacement of one type of well differentiated
tissue with another type of well differentiated tissue, as in Barrett’s
esophagus.
• Necrosis is the unregulated pathologic death of cells resulting from
irreversible damage, as in a diabetic with nephropathy whose foot
has been injured.
http://www.usmle.org/examinations/step1/2010Step1.pdf
Geriatrics, USMLE step exam, apoptosis, menopause, abnormal uterine
bleeding
Abbas, Abul K., Jon C. Aster, Nelson Fausto, and Vinay Kumar. Robbins
and Cotran Pathologic Basis of Disease. 8th ed. Philadelphia: Saunders,
2010.
"apoptosis." Merriam-Webster Online Dictionary. 2010. Merriam-Webster
Online. 17 April 2010
"metamorphosis." Merriam-Webster Online Dictionary. 2010. Merriam-
Webster Online. 17 April 2010
Stedman, Thomas L. Stedman’s Medical Dictionary for the Health
Professions and Nursing Illustrated, 5 th Edition. Baltimore: Lippincott,
Williams, & Wilkins, 2005.
Texas Tech MedCast Producer: Betsy Goebel Jones, Ed.D., betsy.jones@ttuhsc.edu
Prepared for the MS2 Aging Block at Texas Tech University Health Sciences Center School of
Medicine, Andrew Dentino, M.D., Block Director, andrew.dentino@ttuhsc.edu
http://www.ttuhsc.edu/som/fammed/ttmedcast/gerseries/gerstep1prep.aspx