26.10.2012 Views

K - College of Natural Resources - University of California, Berkeley

K - College of Natural Resources - University of California, Berkeley

K - College of Natural Resources - University of California, Berkeley

SHOW MORE
SHOW LESS

You also want an ePaper? Increase the reach of your titles

YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.

third and fourth generations <strong>of</strong> cases (N=43), after the hospital’s imposition <strong>of</strong> limits on<br />

visitors and social contacts.<br />

Smallpox (Variola major), Europe 1958-1973 (Fenner et al. 1988, p. 1077)<br />

This dataset is a summary <strong>of</strong> smallpox importations into Europe from 1958-<br />

1973, and thus combines data collected over a long time period in many countries,<br />

probably with varying degrees <strong>of</strong> smallpox vaccination. Two outbreaks were excluded<br />

from the analysis, because one <strong>of</strong> them had three primary cases and the other had no<br />

primary case (infection was apparently transmitted on a carpet). The remaining<br />

outbreaks each had a single index case, and the number <strong>of</strong> infections in the first<br />

indigenous generation (i.e. cases within Europe) was taken as the Z value for each index<br />

case. Information on later generations is tabulated in the source material, but was<br />

excluded from this analysis because it was unclear if and when control was imposed in<br />

each outbreak, and there is no way to divide the total number <strong>of</strong> cases in the second<br />

indigenous generation among the possible source cases in the first indigenous<br />

generation.<br />

Smallpox (Variola major), Benin 1967 (Henderson and Yekpe 1969)<br />

A village-based outbreak occurred in Benin (formerly Dahomey) in 1967. The<br />

existence <strong>of</strong> the outbreak was concealed from authorities for three months, after which a<br />

vaccination team arrived but is suspected not to have affected the natural die-out <strong>of</strong> the<br />

outbreak. Contact tracing was by recollection <strong>of</strong> the villagers and some links are<br />

uncertain. Vaccination scar rates were 70% among adults.<br />

159

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!