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K - College of Natural Resources - University of California, Berkeley

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decreasing function <strong>of</strong> x for s œ [0,1) and P(X2>x)>P(X1>x) for all x > 0, we have<br />

P(Y1>x)>P(Y2>x) for all x>0. Hence, s)<br />

c ( 1 c)<br />

E(<br />

Y ) c ( 1 c)<br />

E(<br />

Y ) g ( s),<br />

=<br />

+<br />

−<br />

gC C<br />

><br />

( 1<br />

1<br />

2<br />

2<br />

and as argued above we have g 0)<br />

> g ( 0)<br />

for all generations n and therefore<br />

C1<br />

q ><br />

q<br />

C2<br />

.<br />

C n ( C , n<br />

1,<br />

2<br />

To see the utility <strong>of</strong> this claim, let us consider two control strategies C1 and C2<br />

that control two portions <strong>of</strong> the population in different ways. Suppose strategy Ci<br />

*<br />

controls the less-infectious portion <strong>of</strong> the population (i.e. ν < ν ) with probability ai and<br />

*<br />

controls the more-infectious portion <strong>of</strong> the population (i.e. ν ≥ ν ) with probability bi.<br />

In other words,<br />

C<br />

i<br />

( ) ⎨<br />

⎩ ⎧<br />

ν<br />

a<br />

*<br />

if ν < ν<br />

i<br />

= *<br />

b<br />

i<br />

if ν ≥ν<br />

Moreover, let us assume that both strategies control the same fraction <strong>of</strong> individuals, i.e.<br />

∞<br />

∫C<br />

i<br />

0<br />

( u)<br />

f ( u)<br />

du = c<br />

ν<br />

for i=1,2. Suppose that strategy 1 targets more-infectious<br />

individuals to a greater degree than strategy 2, i.e. b1> b2 and thus a1 b<br />

∞<br />

∫<br />

1<br />

ν<br />

∞<br />

∫<br />

2<br />

ν<br />

f<br />

ν<br />

ν<br />

∞<br />

( u)<br />

du = C ( u)<br />

f ( u)<br />

145<br />

du<br />

∫<br />

ν<br />

2<br />

ν<br />

ν<br />

*<br />

∫<br />

0<br />

+<br />

ν<br />

du<br />

−<br />

=<br />

( ) 80

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