27.12.2013 Views

biological sciences HONOURs 2014 - The University of Sydney

biological sciences HONOURs 2014 - The University of Sydney

biological sciences HONOURs 2014 - The University of Sydney

SHOW MORE
SHOW LESS

You also want an ePaper? Increase the reach of your titles

YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.

EVOLUTION OF<br />

VIVIPARITY<br />

45<br />

Research Interests<br />

<strong>The</strong> main focus <strong>of</strong> my research has been on reproduction in<br />

reptiles, with a particular emphasis on the physiology and<br />

ecology <strong>of</strong> eggs and embryos. I have studied eggs <strong>of</strong> all the<br />

major groups <strong>of</strong> reptiles in the world and have recently been<br />

studying viviparous species. My current research is concerned<br />

mainly with the evolution <strong>of</strong> viviparity (live birth) using lizards<br />

as the model. I combine physiology, anatomy and molecular<br />

biology to understand the evolution <strong>of</strong> viviparity across a range<br />

<strong>of</strong> species that have different placental complexities.<br />

Other recent projects in the lab include reproduction in shovelnosed<br />

rays, the physiology and ecology <strong>of</strong> invasive lizards,<br />

sex determination in lizards, physiological ecology <strong>of</strong> flat rock<br />

spiders and feeding behaviour in desert lizards.<br />

Honours projects<br />

I have many opportunities around questions associated with<br />

understanding the evolution <strong>of</strong> live birth, including projects that<br />

would enable you to master a range <strong>of</strong> techniques that could<br />

be used in many fields, including light and electron microscopy,<br />

physiology, immunohistochemistry and molecular biology. I am,<br />

however, willing to entertain ideas for projects in other areas<br />

that embrace combinations <strong>of</strong> physiology, ecology, morphology<br />

Pr<strong>of</strong>essor Mike<br />

Thompson<br />

Room 420, Heydon-<br />

Laurence Building A08<br />

T: (02) 9351 3989<br />

E: mike.thompson@<br />

sydney.edu.au<br />

and molecular biology. If you have idea for projects that you would like to discuss, please send<br />

me an e-mail.<br />

1. Trying to understand the increase in the vascular bed <strong>of</strong> the uterus (angiogenesis), and<br />

a possible link between uterine angiogenesis in lizards and cancer in humans. <strong>The</strong> work has<br />

a large molecular component and includes studies <strong>of</strong> the uterus and embryos <strong>of</strong> lizards, and<br />

work with human cancer cells. It could also involve confocal microscopy. It is collaborative with<br />

Pr<strong>of</strong>essors Chris Murphy and Georges Grau in the School <strong>of</strong> Medical Sciences.<br />

2. Understanding fundamental nutrient transport molecules and morphological features<br />

in the uterus <strong>of</strong> a range <strong>of</strong> species, including marsupials, lizards and snakes. Different<br />

aspects <strong>of</strong> the work involved a combination <strong>of</strong> morphology (scanning and transmission electron<br />

microscopy) and molecular biology (immun<strong>of</strong>luorescent microscopy, Western blotting). It is<br />

collaborative with Pr<strong>of</strong>essor Chris Murphy and Dr Bronwyn McAllan in the School <strong>of</strong> Medical<br />

Sciences.

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!