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biological sciences HONOURs 2014 - The University of Sydney

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MOLECULAR ECOLOGY,<br />

EVOLUTION AND<br />

PHYLOGENETICS<br />

31<br />

Research Interests<br />

Key factors behind the success <strong>of</strong> insects and other arthropods<br />

are the complex interactions they have with microbes, and - in<br />

the case <strong>of</strong> social insects - with each other. I use a combination<br />

<strong>of</strong> molecular, genetic, and bioinformatic tools to investigate<br />

these interactions, across various temporal scales. I have a<br />

general interest in the evolution <strong>of</strong> arthropods, and study a<br />

variety <strong>of</strong> beasties, including three <strong>of</strong> humanity’s favourites:<br />

termites, cockroaches, and ticks.<br />

Honours projects<br />

1. Are Australian ticks spreading Lyme disease? Ticks are<br />

obligate bloodsucking arthropods second only to mosquitoes<br />

as worldwide vectors <strong>of</strong> human diseases. <strong>The</strong> presence in<br />

Australia <strong>of</strong> Lyme borreliosis - the most common tick-borne<br />

disease in the world - is controversial. In this project you will<br />

use molecular techniques to examine Australian ticks for the<br />

presence <strong>of</strong> Borrelia and other potential pathogens.<br />

2. Evolution <strong>of</strong> the heaviest cockroach on earth. How did<br />

Australia’s unique fauna evolve? Macropanesthia rhinoceros is<br />

an endemic Australian cockroach, and also the world’s heaviest.<br />

It digs burrows in the soil up to one metre deep, and gives birth<br />

to live young, both very unique traits among cockroaches. <strong>The</strong><br />

Associate Pr<strong>of</strong>essor<br />

Nate Lo<br />

Room 306, Edgeworth-<br />

David Building A11<br />

T: (02) 9036 7649<br />

E: nathan.lo@sydney.<br />

edu.au<br />

aim <strong>of</strong> this project is to study how and when this species evolved, by sequencing its DNA and<br />

performing phylogenetic comparisons with related cockroaches. <strong>The</strong> student will gain experience<br />

with molecular ecological techniques, and computational techniques used in evolutionary biology.<br />

3. Potential fitness cost associated with insecticide resistance in aphids. Fitness costs have<br />

been associated with antibiotic resistance in bacterial as well as insecticide resistance in pests <strong>of</strong><br />

agriculture. Aphids are a major pest <strong>of</strong> agricultural and horticultural crops worldwide, and some<br />

species have developed resistance to commonly used insecticides. This project, in collaboration<br />

with NSW Department <strong>of</strong> Primary Industries, will involve setting up and maintenance <strong>of</strong> colonies<br />

<strong>of</strong> an aphid species resistant to the insecticide pirimicarb. Colonies will be tracked over time for<br />

their resistance status via insecticide bioassay and/or qPCR.

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