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INVESTIGATIONS INTO HYPERLIPIDEMIA AND ITS POSSIBLE ...

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47<br />

nutrient delivery (which also mainly is related to dogs with acute pancreatitis), and the<br />

type of diet administered, which might be important in dogs with both acute and chronic<br />

pancreatitis. Although the diet of choice for the management of dogs with pancreatitis<br />

has not been systematically studied to date, based on anecdotal experience, a balanced<br />

ultra-low-fat diet is currently the preferred choice for dogs. This is mainly based on<br />

studies that suggest that high-fat diets (typically table scraps) might be related to the<br />

development of pancreatitis in some dogs. 252 This is further supported by studies that<br />

implicate hypertriglyceridemia in the development of pancreatitis in humans and<br />

experimental models. 252 However, no studies have evaluated whether the fat content of<br />

commercially available canine diets is important in treating or preventing acute and<br />

chronic pancreatitis. While several supportive measures are important in the<br />

management of acute pancreatitis, nutritional management might be the only measure<br />

for the long-term management of dogs with chronic pancreatitis.<br />

The association between hyperlipidemia and pancreatitis<br />

An association between hyperlipidemia and pancreatitis was first noted in<br />

humans by Speck in 1865. 253 Several clinical and experimental studies in humans and<br />

animals, respectively, have been conducted since then, and today, severe<br />

hypertriglyceridemia is a well recognized risk factor for pancreatitis in humans. 254-257<br />

Hypertriglyceridemia is believed to be the 3rd most common cause of pancreatitis in<br />

humans, after alcohol- and gallstone-induced pancreatitis, accounting for up to 10% of<br />

cases. 258<br />

However, within specific groups, the prevalence of hypertriglyceridemia-

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