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INVESTIGATIONS INTO HYPERLIPIDEMIA AND ITS POSSIBLE ...

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46<br />

factors should always be investigated in dogs with pancreatitis. If any of these factors are<br />

present, they should be managed as possible.<br />

Other than that, the treatment of pancreatitis in dogs remains almost exclusively<br />

supportive and symptomatic. Fluid therapy, in some cases including plasma transfusion,<br />

is considered important in both humans and dogs with severe disease and hypovolemia<br />

and/or dehydration. 165,196,208-215 Pain management is also considered crucial in cases of<br />

both acute and chronic pancreatitis, when pain is present. 216-218 The use of antiemetic<br />

medications is recommended in cases of pancreatitis where vomiting is present. 219-221<br />

Routine antibiotic therapy is highly controversial and it is usually not recommended in<br />

dogs unless an infection is present. 155,208,222-225<br />

Finally, surgical intervention of<br />

pancreatitis is rarely recommended in dogs unless certain complications occur (such as<br />

pancreatic abscess, pancreatic pseudocyst, or extrahepatic biliary tract obstruction). 226-237<br />

A plethora of other therapeutic agents have been recommended by some authors in both<br />

veterinary and human medicine. 238-240<br />

but there is currently no convincing evidence that<br />

any of these agents is beneficial for the treatment of spontaneous pancreatitis in dogs.<br />

The role of nutrition in the management of pancreatitis needs some attention. The<br />

nutritional approach of humans with pancreatitis (especially acute pancreatitis) has been<br />

the focus of extensive basic and clinical research for several decades.<br />

241-243<br />

Unfortunately, studies in dogs suffering specifically from either acute or pancreatitis are<br />

sparse and therefore the nutritional approach in these cases is based on clinical<br />

experience. 244-251 Questions regarding the nutritional approach of dogs with pancreatitis<br />

have to do with the timing of feeding during an episode of acute pancreatitis, the route of

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