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INVESTIGATIONS INTO HYPERLIPIDEMIA AND ITS POSSIBLE ...

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35<br />

The combination of vomiting and abdominal pain, although suggestive of pancreatitis, is<br />

also seen with other diseases (e.g., gastrointestinal foreign bodies, peritonitis). Other<br />

possible findings include shock, hypothermia, a cardiac murmur, tachycardia, bleeding<br />

diathesis, ascites, a palpable abdominal mass, and/or harsh lung sounds. 64 Patients with<br />

less severe or chronic pancreatitis typically manifest less profound clinical signs, such as<br />

anorexia and depression, or might even be subclinical.<br />

Clinical pathology 64,175<br />

Results of complete blood count (CBC), serum biochemistry profile, and<br />

urinalysis are nonspecific, and thus of limited usefulness for the diagnosis of pancreatitis<br />

in dogs. However, these tests should always be performed in dogs with suspected<br />

pancreatitis because they are useful for ruling out other differential diagnoses and also<br />

provide important information about the systemic condition of the animal.<br />

Often, especially in mild cases, the CBC, serum biochemistry profile, and<br />

urinalysis are normal. Possible hematologic findings in dogs with pancreatitis include<br />

anemia or hemoconcentration, leukocytosis or leucopenia, and thrombocytopenia.<br />

Evidence of coagulopathy, such as prolonged activated clotting time (ACT),<br />

prothrombin time (PT), and/or partial thromboplastin (PTT) time, are seen in some<br />

cases, and may or may not be associated with spontaneous bleeding. In other cases, there<br />

might be clinical evidence suggestive of DIC, such as thrombocytopenia, prolongation of<br />

clotting times (i.e., ACT, PT, PTT), and a positive d-dimer test. Different combinations<br />

of increases in liver enzyme activities and hyperbilirubinemia are common and might

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