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INVESTIGATIONS INTO HYPERLIPIDEMIA AND ITS POSSIBLE ...

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22<br />

Dietary management<br />

Typically, the first step in the management of primary hyperlipidemia is dietary<br />

modification. 31,33,49,52 Dogs with primary hyperlipidemia should be offered a low-fat diet<br />

throughout their lives. 33 Diets that contain less than 25 g of fat per 1,000 Kcal are<br />

recommended. 31,33,131<br />

Many commercially available diets are suitable for dogs with<br />

primary hyperlipidemia. Also, many home-made low-fat diets (e.g., boiled lean turkey<br />

breast and rice) are suitable for these dogs, but care should be taken to make sure that<br />

these diets are balanced. Treats and table scraps should be avoided unless they are low in<br />

fat. 131 Serum lipid concentrations should be re-evaluated after feeding a low-fat diet for<br />

about 3-4 weeks. 33 If the serum triglyceride concentration has decreased to < 500 mg/dL,<br />

dietary therapy should be continued and the new diet should be offered for the rest of the<br />

animal’s life, and serum triglyceride concentrations should be re-evaluated intermittently<br />

every 6 months. 33 In dogs that do not sufficiently respond to low-fat diets, an ultra lowfat<br />

diet (< 20 g of fat per 1,000 Kcal) can be offered, or medical treatment can be<br />

initiated. 131<br />

Medical management<br />

Some dogs with primary hyperlipidemia will not sufficiently respond to feeding a<br />

low or ultra low-fat diet alone, especially when hypertriglyceridemia is due to<br />

endogenously formed triglycerides. 32-34,83 In these cases, medical treatment is required in<br />

addition to the low-fat diet in an effort to effectively reduce serum lipid<br />

concentrations. 32,83 It needs to be pointed out that no studies have evaluated the efficacy

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