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INVESTIGATIONS INTO HYPERLIPIDEMIA AND ITS POSSIBLE ...

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might affect lipid metabolism (hypothyroidism, pancreatitis, pregnancy). Thus, 16 dogs<br />

completed the study.<br />

The 16 dogs that completed the study had a median BCS of 5 (range: 4 to 6) and<br />

a median age of 8.5 years (range: 6.7 to 11.9 years). Eleven dogs were female (all<br />

spayed) and 5 dogs were male (all castrated).<br />

Group 2 consisted of 28 Miniature Schnauzers that had a median BCS of 5<br />

(range: 4 to 6) and a median age of 9.1 years (range: 7.1 to 12.2 years). Fourteen dogs<br />

were female (8 spayed) and 14 dogs were male (5 castrated).<br />

Serum triglyceride, cholesterol, and Spec cPL concentrations in Group 1<br />

Analysis using the Friedman’s test (repeated measures non-parametric 1-way<br />

ANOVA) showed that serum triglyceride concentrations before the diet change (median<br />

of sample 1: 480 mg/dL; median for sample 2: 493 mg/dL) were significantly higher<br />

than after the diet change (median of sample 3: 177 mg/dL; median for sample 4: 168<br />

mg/dL; P=0.0001; Figure 16). Dunn’s post-test indicated that there were no significant<br />

differences between samples 1 and 2 (i.e., while dogs were on their original diets) or<br />

between sample 3 and 4 (i.e., while dogs were on the study diet). There were significant<br />

differences between samples before and after the diet change (P500 mg/dL in Group 1

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