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visible staining were accounted as live cells (Fig. 25). The results of this study were
presented as a ratio between the number of apoptotic cells per 100 cells counted in 10
different fields (Fig. 26).
Adriamycin alone increased apoptosis by about 10}o/o, while trolox modulated
this increase. A treatment with 0.1 pM concentration of retinoic acid resultedin a35o/o
decrease in the occtlrïence of apoptosis when compared to the control (Fig. 26). Retinoic
acid (0.1pM) significantly decreased the apoptosis caused by adriamycin. 1 pM RA alone
caused an increase in apoptosis when compared to the CONT group but this increase was
well below the ADR group value (Fig. 26). In the ADR+IRA group the percent apoptotic
count was not significantly different when compared to the ADR group (Fig. 26).
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