in partial fulfil]ment of the - MSpace - University of Manitoba
in partial fulfil]ment of the - MSpace - University of Manitoba
in partial fulfil]ment of the - MSpace - University of Manitoba
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70<br />
TÀBIE 1 9<br />
Comparison <strong>of</strong><br />
scores <strong>of</strong> dark adaptation test parameters and serum<br />
Vitam<strong>in</strong> À Ievel.<br />
Dark Àdaptation<br />
Test Parameters<br />
Subj ec t s<br />
Controls<br />
Vitam<strong>in</strong> A<br />
sufficient<br />
patients<br />
Vitam<strong>in</strong> A<br />
deficient<br />
patients<br />
Rapid Dark Ädaptation<br />
Test Time (<strong>in</strong> m<strong>in</strong>utes)<br />
4.4110.83<br />
4 . 59r0. 97<br />
7 .63!1 .79<br />
Rod-cone Break<br />
Time (<strong>in</strong> m<strong>in</strong>utes)<br />
8.0r0.7<br />
5.711.1<br />
9.611.8<br />
F<strong>in</strong>al Dark Adapted<br />
Threshold (1og/ca/mz )<br />
-4 "9!0 .2<br />
-4.9!0.2<br />
-4.4!0 .4<br />
Serum Vitam<strong>in</strong> À<br />
( <strong>in</strong> ug/dI )<br />
45r'11<br />
44r1 3<br />
26!8<br />
(Vi. nton and Russell , 1 981 )<br />
1980). Subjects for this study were adult patients with liver disease,<br />
gastro-ínLest<strong>in</strong>al disease and chronic alcoholism. Each subject had a<br />
normal ophthalmoscopic exam. Blood samples were collected and serum<br />
Vitam<strong>in</strong> A levels were determ<strong>in</strong>ed. Dark adaptation abiliLy was measured<br />
us<strong>in</strong>g <strong>the</strong> Classical Dark Adaptation Test. Comparison <strong>of</strong> serum Vitam<strong>in</strong> A<br />
levels and <strong>the</strong> f<strong>in</strong>al dark adapted threshold revealed that a serum<br />
Vitam<strong>in</strong> A level <strong>of</strong> >40 ug/dl predicted normal dark adaplation 95% <strong>of</strong> <strong>the</strong><br />
time. À serum Vitam<strong>in</strong> a level <strong>of</strong> >30 ug/d1 predicted normal dark adaptation<br />
68% <strong>of</strong>. <strong>the</strong> time and a level <strong>of</strong>. >20 ug/dl predicted normal dark<br />
adaptation 27% <strong>of</strong> <strong>the</strong> time (Carney and Russell, 1980)"