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in partial fulfil]ment of the - MSpace - University of Manitoba

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70<br />

TÀBIE 1 9<br />

Comparison <strong>of</strong><br />

scores <strong>of</strong> dark adaptation test parameters and serum<br />

Vitam<strong>in</strong> À Ievel.<br />

Dark Àdaptation<br />

Test Parameters<br />

Subj ec t s<br />

Controls<br />

Vitam<strong>in</strong> A<br />

sufficient<br />

patients<br />

Vitam<strong>in</strong> A<br />

deficient<br />

patients<br />

Rapid Dark Ädaptation<br />

Test Time (<strong>in</strong> m<strong>in</strong>utes)<br />

4.4110.83<br />

4 . 59r0. 97<br />

7 .63!1 .79<br />

Rod-cone Break<br />

Time (<strong>in</strong> m<strong>in</strong>utes)<br />

8.0r0.7<br />

5.711.1<br />

9.611.8<br />

F<strong>in</strong>al Dark Adapted<br />

Threshold (1og/ca/mz )<br />

-4 "9!0 .2<br />

-4.9!0.2<br />

-4.4!0 .4<br />

Serum Vitam<strong>in</strong> À<br />

( <strong>in</strong> ug/dI )<br />

45r'11<br />

44r1 3<br />

26!8<br />

(Vi. nton and Russell , 1 981 )<br />

1980). Subjects for this study were adult patients with liver disease,<br />

gastro-ínLest<strong>in</strong>al disease and chronic alcoholism. Each subject had a<br />

normal ophthalmoscopic exam. Blood samples were collected and serum<br />

Vitam<strong>in</strong> A levels were determ<strong>in</strong>ed. Dark adaptation abiliLy was measured<br />

us<strong>in</strong>g <strong>the</strong> Classical Dark Adaptation Test. Comparison <strong>of</strong> serum Vitam<strong>in</strong> A<br />

levels and <strong>the</strong> f<strong>in</strong>al dark adapted threshold revealed that a serum<br />

Vitam<strong>in</strong> A level <strong>of</strong> >40 ug/dl predicted normal dark adaplation 95% <strong>of</strong> <strong>the</strong><br />

time. À serum Vitam<strong>in</strong> a level <strong>of</strong> >30 ug/d1 predicted normal dark adaptation<br />

68% <strong>of</strong>. <strong>the</strong> time and a level <strong>of</strong>. >20 ug/dl predicted normal dark<br />

adaptation 27% <strong>of</strong> <strong>the</strong> time (Carney and Russell, 1980)"

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