Fikireselassie Samuel.pdf - Addis Ababa University
Fikireselassie Samuel.pdf - Addis Ababa University
Fikireselassie Samuel.pdf - Addis Ababa University
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Table of Contents<br />
Page<br />
ACKNOWLEDGEMENTS................................................................................................iii<br />
List of Tables............................................................................................................................... iv<br />
List of Figures..............................................................................................................................v<br />
List of Abbreviations and Acronyms........................................................................................vi<br />
List of Appendices......................................................................................................................vii<br />
ABSTRACT...........................................................................................................................viii<br />
1. INTRODUCTION …..………………………………………………….…..….…….....1<br />
1.1.Burden of Soil-transmitted Helminthiasis……………...…………………....2<br />
1.2.Soil-transmitted Helminth Infections……………………................................3<br />
1.3.Soil-transmitted Helminth Infections in Ethiopia………………................6<br />
1.4.Impact of Soil-transmitted Helminths on Human Health………............6<br />
1.5.Anthelminthics…………………………………….……………………....……..…7<br />
1.5.1. Anthelminthic Efficacy in Human Helminthiasis……..……..……..…........ 10<br />
1.5.2. Assessment of Drug Efficacy………………………………........................... 11<br />
1.5.3. Standard Method to Evaluate Efficacy…………………………………...…11<br />
1.5.4. Mechanism of Anthelminthic Drug Resistance…………………………..... 12<br />
1.5.5. Drug Resistance in Nematodes…………………………….……………...….13<br />
2. STATEMENT OF THE PROBLEM……………………………………….....…14<br />
3. HYPOTHESIS………………………………………………….………………..……15<br />
4. OBJECTIVES ……………………………………………………….…………….... 16<br />
4.1.General Objective…………………………………………….……………...…..16<br />
4.2. Specific Objectives………………………………………….…………….…..….16<br />
5. MATERIAL AND METHODS…………….………………………….…….……16<br />
5.1. Study Area...………………………………………………….……………..…..…16<br />
5.2.Study Population………………………….………………………………….......17<br />
i<br />
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