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Our sense organs 45

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total anatomy and physiology of a human being,<br />

but also our numerous predispositions and gifts.<br />

For example, musical ability, aggressiveness, or<br />

language aptitude. Are the non-material characteristics<br />

of people, for example, the ability to<br />

love, or experience joy, in fact reducible to being<br />

described by a nucleotide sequence? Here we still<br />

face major scientific mysteries.<br />

Information processing: <strong>Our</strong> 30,000 genes provide<br />

exact instructions to each cell for manufacturing<br />

everything required for it to carry out the<br />

role for which it is programmed; whether hormones,<br />

enzymes, mucus, sebum, the weapons of<br />

the immune system, or the impulses in the nerve<br />

cells of the central nervous system.<br />

One might well ask at this point: How is this<br />

information decoded, and how are these abstract<br />

“words” translated into concrete protein molecules?<br />

This never-ending process takes place<br />

inside an unimaginably small space, namely<br />

within the cells, each measuring only a few hundredths<br />

of a millimetre. Special protein molecules<br />

locate a particular piece of information – a gene –<br />

copy it, and prepare a messenger, a chemical relative<br />

of DNA called messenger-RNA. This mRNA<br />

then travels from the control centre in the nucleus<br />

out into the cytoplasm, to the ribosomes.<br />

These small granular bodies are where protein<br />

synthesis takes place. When these RNA messengers<br />

arrive here, they specify the sequence in<br />

which the 20 types of amino acids, the building<br />

blocks of all proteins, are to be assembled. Protein<br />

molecules are constructed here “block by<br />

block”, just as a house is built brick by brick; they<br />

are subsequently dispatched to carry out their<br />

various vital functions.<br />

The next important step, namely the formation of<br />

specific structures like cells and <strong>organs</strong> from<br />

these protein molecules, is very complex, and is<br />

not yet fully understood. But we do know that it<br />

is somehow encoded in our genes * , and it largely<br />

determines what we are. <strong>Our</strong> genes ensure that<br />

we become human beings rather than animals.<br />

<strong>Our</strong> gender, the colour of our eyes, skin and hair,<br />

and to a great extent our size, are all determined<br />

by our personal genome. It sets parameters for<br />

our intelligence and, to a large extent, determines<br />

our never-to-be-repeated unique personality. All<br />

these patterns are set at the precise moment in<br />

which the male chromosomes in a sperm cell<br />

meet up with those of a female egg cell (ovum).<br />

The moment of fertilisation truly is the starting<br />

point of our life.<br />

A comparison: Each of our approximately 100<br />

million million (10 14 ) cells has the following main<br />

components: a cell membrane, many pores and<br />

channels in this membrane, many mitochondria<br />

for regulating the flow of energy, many ribosomes<br />

which translate genetic information into<br />

proteins, and a nucleus containing the genetic<br />

information in the form of DNA.<br />

Nowadays many people are familiar with the<br />

parts of a personal computer (PC), like hard disk,<br />

read/write head, interface, and network card. To<br />

explain the performance and complex functioning<br />

of a biological cell, Zoltán Takács, a biophysicist,<br />

compared the processing and storage of information<br />

in a cell with what happens inside a<br />

computer. If a cell in simplified form is regarded<br />

as a computer, we have the following analogies:<br />

– The cell membrane would be the computer<br />

housing, but it is only 10 nanometres thick<br />

(= one hundred thousandth of a millimetre).<br />

– The pores and channels are the interfaces.<br />

– The mitochondria comprise 800 network<br />

cards.<br />

– A ribosome would be a central processing<br />

unit (CPU), but a biological cell has more than<br />

six million CPUs.<br />

– The nucleus would correspond to a hard drive.<br />

There would then be 23 different hard disks<br />

(= chromosomes), each of which has its own<br />

backup disk. The storage capacities of these<br />

23 disks add up to about 1 Gigabyte. Biological<br />

“hard disks” are actually not hard, but can perhaps<br />

be regarded more like ”floppy disks”; the<br />

46 strands of DNA do not rotate around<br />

a fixed spindle, but occur as loose clusters in<br />

the nucleus.<br />

– The diameter of this biological computer is<br />

about 20 micrometres (= two hundredths of<br />

a millimetre).<br />

77

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