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with a diameter of only 7 µm = 0.007 mm. The<br />
tiny vessels in this clump (about 30 loops; see the<br />
right hand part of the diagram on page 69) subsequently<br />
combine to form the vas efferens<br />
which carries the blood away. This is a marvellously<br />
constructed system.<br />
The tuft of blood vessels is enclosed in a doublewalled<br />
container known as Bowman’s capsule,<br />
whose diameter is only about 0.17 mm. The place<br />
where the blood enters and leaves, is called the<br />
vascular pole. The urinary pole, where a single<br />
conduit emerges, is located at the other end of<br />
1<br />
Vas afferens, vas efferens (Latin vas = vessel;<br />
affere = bring in; effere = take away): The vas afferens<br />
leads from the interlobular arteries into the renal<br />
glomerulus, and the vas efferens leads back out of<br />
the glomerulus.<br />
the capsule. The walls of the looped capillaries<br />
act like a filter with extremely fine pores. These<br />
allow water and other small molecules to be<br />
squeezed out through them, but blood corpuscles<br />
and large protein molecules cannot pass through.<br />
The result of this ultra-filtration is that 180 litres<br />
of “primary” urine is pressed from 1,700 litres of<br />
blood during a 24 hour period, comprising a loss<br />
of about 10 per cent by volume. But most of this<br />
“loss” is recovered by means of the retro-absorption<br />
taking place in the renal tubules, tiny tubes<br />
which extend from the urinary poles of the capsules.<br />
Water, glucose, and other substances are<br />
recovered from the primary urine and returned to<br />
the blood. A renal tubule starts with a convoluted<br />
segment which joins directly to a straight seg-<br />
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Renal artery<br />
Adrenal gland<br />
Renal vein<br />
Ureter<br />
Aorta<br />
Inferior vena cava<br />
Renal cortex<br />
Renal pyramid<br />
Renal pelvis<br />
68<br />
Minor renal calyx<br />
Renal capsule<br />
Glomeruli in the cortex<br />
Major renal calyx<br />
Renal medulla