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Acute Diarrhea Evaluation in Primary Care Acute Diarrhea luation in ...

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Calicivirus<br />

• 90% of epidemic gastroenteritis<br />

• Norwalk, Saporo, etc virus<br />

• =norovirus<br />

• Cannot grow virus <strong>in</strong> cell culture­study by<br />

• EIA for antibody and stool antigen,<br />

• or more recently by RT­PCR<br />

• Immunity short­term term and genotype<br />

• specific—repeat <strong>in</strong>fections; vacc<strong>in</strong>e<br />

• will be problematic (attempts underway)<br />

• Prolonged excretion of virus; secondary cases

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