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Mitral Valve Repair in Children

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<strong>Mitral</strong> <strong>Valve</strong> <strong>Repair</strong> <strong>in</strong> <strong>Children</strong><br />

S. Buz, R. Hetzer<br />

Deutsches Herzzentrum Berl<strong>in</strong>, Germany<br />

DHZB-cw/ 2009


Deutsches Herzzentrum Berl<strong>in</strong><br />

4/1986 – 6/2009<br />

All valve operations 21.723<br />

mech. biol. repair<br />

Aortic valve surgery 4.651 7.240 724<br />

<strong>Mitral</strong> valve surgery 2.090 1.855 3.820<br />

Tricuspid valve surgery 80 103 1.314<br />

Pulmonary valve surgery 17 604 240<br />

Multiple valve operations <strong>in</strong> 1041 cases<br />

S<strong>in</strong>ce 2007 Transfemoral PVR (Melody ®) 35<br />

S<strong>in</strong>ce 2008 Transapical AVR (Sapien ® )<br />

125<br />

Transfemoral + transapical, t.axillary 11<br />

(Sapien ® , Corevalve ® )<br />

DHZB-cw/ 2009


DHZB Guidl<strong>in</strong>e MVR<br />

►Any mitral valve reconstruction must lead to a primarily<br />

optimal result with an expected durability of at least 10 to 15<br />

years.<br />

►Excepted t d from this rule are children and patients t with active,<br />

<strong>in</strong>fectious endocarditis.<br />

►In all cases where there is doubt about the result of a<br />

reconstruction, prosthesis must be preferred.<br />

►Patients t can benefit from less traumatic, ti „m<strong>in</strong>imal i <strong>in</strong>vasive“<br />

i operations, if no compromise has to be made concern<strong>in</strong>g the<br />

orig<strong>in</strong>al goal of the operation.<br />

►In chronic or <strong>in</strong>termittent atrial fibrillation endo-atrial<br />

ablation is added as a rule.<br />

DHZB-cw/ 2009


Heart <strong>Valve</strong> Surgery – The Biological Concept<br />

Pr<strong>in</strong>ciples of <strong>Mitral</strong> <strong>Valve</strong> <strong>Repair</strong><br />

►Primary repair should be reached by sutures only. The<br />

pericardial strip should not lead to further anulus<br />

shorten<strong>in</strong>g, however, should stabilize the suturedependent<br />

repair and <strong>in</strong>crease the height of the posterior<br />

leaflet coaptation counterpart. This is particularily<br />

important <strong>in</strong> ischemic mitral <strong>in</strong>competence<br />

►Secure anchorage of runn<strong>in</strong>g sutures, pericardial<br />

pledgets and pericardial strip by additional sutures<br />

DHZB-cw/ 2009


Criteria for <strong>Mitral</strong> <strong>Repair</strong><br />

positive +/- negative<br />

Tender Leaflet Body ++<br />

Reduced d Mobility PML +<br />

AML ++<br />

Calcium Commissure +<br />

Leaflet Body +<br />

Post. Anulus +<br />

Chordal Rupture PML ++<br />

AML +<br />

Leaflet Perforation +<br />

DHZB-cw/ 2009


<strong>Mitral</strong> valve surgery –<br />

the approaches<br />

DHZB-cw/ 2009


DHZB-cw/ 2009


M<strong>in</strong>imal-<strong>in</strong>vasive <strong>Mitral</strong> Surgery<br />

DHZB-cw/ 2009


DHZB-cw/ 2009


DHZB-cw/ 2009


DHZB-cw/ 2009


DHZB-cw/ 2009


<strong>Mitral</strong> valve repair –<br />

some risks and some precautions<br />

DHZB-cw/ 2009


Ruptured Chordae of Posterior Leaflet<br />

DHZB-cw/ 2009


Gerbode Plasty – Coronary K<strong>in</strong>k<strong>in</strong>g<br />

DHZB-cw/ 2009


Hazard of Coronary K<strong>in</strong>k<strong>in</strong>g <strong>in</strong><br />

Lateral Annuloplasty<br />

DHZB-cw/ 2009


Hazard of Coronary K<strong>in</strong>k<strong>in</strong>g <strong>in</strong><br />

Lateral Anuloplasty<br />

DHZB-cw/ 2009


DHZB-cw/ 2009


Mechanism of SAM <strong>in</strong> Excessive Annular Shorten<strong>in</strong>g<br />

DHZB-cw/ 2009


<strong>Mitral</strong> valve repair <strong>in</strong> childhood<br />

DHZB-cw/ 2009


<strong>Mitral</strong> <strong>Valve</strong> <strong>Repair</strong> <strong>in</strong> <strong>Children</strong> (Personal Series)<br />

DHZB 06/1987 – 05/2009<br />

130 children<br />

<strong>Children</strong> age range<br />

1 mo. – 17 yrs.<br />

Mean age<br />

6.8 yrs.<br />

Mdi Median age<br />

60 6.0 yrs.<br />

Male n = 67<br />

Female n = 63<br />

≤ 30 days mortality = 4 / 130 = 3.0%<br />

DHZB-cw/ 2009


<strong>Mitral</strong> <strong>Valve</strong> Lesions <strong>in</strong> Childhood<br />

►Congenital n = 83 ►Acquired n = 47<br />

Cleft 38<br />

Parachute 11<br />

Hammock 8<br />

Bland-White-Garland-Syndr Syndr. 4<br />

Membrane 5<br />

MV-Dysmorphy y 5<br />

Marfan-Syndrome 5<br />

Annular Dilation 3<br />

S<strong>in</strong>gle AV-<strong>Valve</strong> 1<br />

MV Stenosis 1<br />

Floppy <strong>Valve</strong> Syndrome 2<br />

HOCM 14<br />

Endocarditis 11<br />

Rheumatic fever 12<br />

DCM 7<br />

After chest trauma 1<br />

Leaflet et perforation o 1<br />

Rupture of Chordae 1<br />

DHZB-cw/ 2009


Hetzer R, Delmo-Walter E, Hübler M, Alexi-Meskishvili V, Weng Y, Nagdyman N, Berger F.<br />

Annals of Thoracic Surgery 2008;86(2):604-13.<br />

DHZB-cw/ 2009


Annular Dilatation<br />

before Reconstruction<br />

DHZB-cw/ 2009


Modified Kay-Wooler annuloplasty<br />

for annular dilatation <strong>in</strong> small <strong>in</strong>fants<br />

DHZB-cw/ 2009


Modified Gerbode plication plasty<br />

for ruptured chordea of posterior leaflet<br />

DHZB-cw/ 2009


Video 2 m<strong>in</strong><br />

DHZB-cw/ 2009


Modified Paneth Plasty<br />

(Hetzer R, <strong>in</strong> Borst HG (ed) Herzchirurgie 1991 )<br />

DHZB-cw/ 2009


Modified Paneth Annuloplasty<br />

for dilated annulus<br />

Posterior annulus<br />

shorten<strong>in</strong>g plasty<br />

Re<strong>in</strong>forcement with<br />

autologous pericardial<br />

strip (Hetzer modification)<br />

Completed repair<br />

DHZB-cw/ 2009


Video 2 m<strong>in</strong><br />

DHZB-cw/ 2009


Video<br />

DHZB-cw/ 2009


MVR-Paneth+autologous autologous pericardial strip, left auricula occlusion,<br />

Maze operation<br />

DHZB-cw/ 2009


Recurrent <strong>Mitral</strong> Incompetence 8.4 years after<br />

<strong>in</strong>itial iti Paneth Suture <strong>Repair</strong> at 2.1 years of age<br />

DHZB-cw/ 2009


Repeat Paneth and Pericardial Strip Plasty<br />

DHZB-cw/ 2009


Hammock valve<br />

Absence of papilary muscle<br />

DHZB-cw/ 2009


<strong>Repair</strong> of Hammock valve<br />

Before repair<br />

Splitt<strong>in</strong>g of a<br />

papillary muscle<br />

After repair<br />

DHZB-cw/ 2009


Hypertrophic obstructive cardiomyopathy<br />

and<br />

the mitral valve<br />

DHZB-cw/ 2009


HOCM: Parasternal long axis view<br />

Preoperative<br />

After surgery<br />

LVOT<br />

SAM<br />

DHZB-cw/ 2009


HOCM: Short axis view<br />

Bevor surgery<br />

After surgery<br />

30 mm<br />

11 mm<br />

DHZB-cw/ 2009


HOCM: Peroperative color Doppler<br />

Parasternal long axis view<br />

DHZB-cw/ 2009


Anterior leaflet retention plasty (ALRP)<br />

for HOCM and systolic anterior motion (SAM)<br />

A: Septal myectomy<br />

(aortic view)<br />

B: ALRP (Hetzer technique)<br />

C: completed repair<br />

(atrial view)<br />

D: <strong>Mitral</strong> <strong>in</strong>sufficiency <strong>in</strong><br />

HOCM and SAM (preop.)<br />

E: postoperative<br />

DHZB-cw/ 2009


HOCM and <strong>Mitral</strong> regurgitation<br />

DHZB-cw/ 2009


HOCM and <strong>Mitral</strong> regurgitation<br />

Myectomy<br />

DHZB-cw/ 2009


HOCM<br />

DHZB-cw/ 2009


HOCM<br />

DHZB-cw/ 2009


HOCM<br />

<strong>Mitral</strong> valve repair (ALRP)<br />

DHZB-cw/ 2009


HOCM<br />

<strong>Mitral</strong> valve repair (ALRP)<br />

DHZB-cw/ 2009


HOCM: Postoperative ECHO with CW Doppler<br />

DHZB-cw/ 2009


<strong>Mitral</strong> <strong>Valve</strong> <strong>Repair</strong> <strong>in</strong> Childhood<br />

Freedom from Reoperation<br />

DHZB-cw/ 2009


<strong>Mitral</strong> <strong>Valve</strong> <strong>Repair</strong> <strong>in</strong> Childhood<br />

Survival<br />

DHZB-cw/ 2009


<strong>Mitral</strong> <strong>Valve</strong> <strong>Repair</strong> <strong>in</strong> Childhood<br />

Survival by Age Group<br />

DHZB-cw/ 2009


<strong>Mitral</strong> <strong>Valve</strong> <strong>Repair</strong> <strong>in</strong> Childhood<br />

1. <strong>Mitral</strong> <strong>Repair</strong> is the preferred technique for any k<strong>in</strong>d of mitral<br />

disease <strong>in</strong> childhood<br />

2. This avoids the difficulty of valve replacement e <strong>in</strong> particular a <strong>in</strong><br />

<strong>in</strong>fants and small children <strong>in</strong> the face of complete lack of a<br />

prosthesis suitable for this age group<br />

3. Even when the primary repair result is not optimal, time can<br />

be ga<strong>in</strong>ed for later-on repeated repair until a def<strong>in</strong>ite adult<br />

size prosthesis can be implanted<br />

4. <strong>Repair</strong> allows for valve growth, no need of anticoagulation<br />

and has very little thrombotic risk<br />

DHZB-cw/ 2009


<strong>Mitral</strong> <strong>Valve</strong> <strong>Repair</strong> <strong>in</strong> Childhood<br />

5. This is best achieved by a spectrum of repair techniques<br />

applied <strong>in</strong>dividually and which avoid any k<strong>in</strong>d of prosthetic<br />

material<br />

6. Stabilisation of repair with autologous pericardial<br />

strip has rema<strong>in</strong>ed so far without re-operation<br />

7. <strong>Mitral</strong> valve area obviously grows along the anterior<br />

leaflet anulus<br />

DHZB-cw/ 2009


Thank you!!<br />

DHZB-cw/ 2009


DHZB-cw/ 2009


DHZB-cw/ 2009


<strong>Repair</strong> of Parachute ac <strong>Valve</strong><br />

DHZB-cw/ 2009


DHZB-cw/ 2009


DHZB-cw/ 2009


DHZB-cw/ 2009


DHZB-cw/ 2009


Techniques of AV-<strong>Valve</strong> Reconstruction<br />

DHZB-cw/ 2009


Techniques of AV-<strong>Valve</strong> Reconstruction<br />

DHZB-cw/ 2009

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