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Marine Ecosystems Research Department - jamstec japan agency ...

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JAMSTEC 2002 Annual Report<br />

Frontier <strong>Research</strong> System for Extremophiles<br />

2. Studies on applications of microorganisms<br />

To have effective collaboration researches with<br />

companies our frontier researches are focused on finding<br />

out the seeds of attractive applications. To achieve<br />

this goal, studies on functionality of genes, substances,<br />

proteins, and useful enzymes from the deep sea, earth's<br />

crust, and special environments are the first step.<br />

Further characterization and finding applications of the<br />

above will be done as the next steps. So far, we have<br />

discovered highly alkaline α-amylases, highly alkaline<br />

CGTases, new mannanases, a super-alkaline protease,<br />

new agarases, and useful enzymes from genome<br />

sequences. Analyzing and genetic engineering of a<br />

high alkaline proteases, development of enzymes using<br />

for production of oligo-saccharides, post-genome studies<br />

of Bacillus halodurans (pH adaptation), and crystallization<br />

of useful enzymes are also in progress.<br />

3. Collaboration researches with companies<br />

Currently, collaboration with companies, including<br />

pharmaceutical, food, chemical, computer soft, and<br />

off-scouring treatment companies, have resulted in the<br />

dispatch of researchers to our center for joint research.<br />

86

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