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Coagulation Made Simple

Coagulation Made Simple

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Heparin- Induced<br />

Thrombocytopenia<br />

• Treatment<br />

– Stop all heparin products<br />

– Allow the heparin effect to<br />

wear off [ongoing<br />

prothrombotic state –<br />

micro-particles]<br />

– Warfarin contraindicated<br />

until adequate alternative<br />

anticoagulation established<br />

• Prothrombotic state similar to that<br />

of warfarin-induced protein<br />

C/S deficiency<br />

• May lead to venous gangrene or<br />

worse

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