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Coagulation Made Simple

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FVIIa<br />

• Anticoagulant reversal agent?<br />

– Hemorrhage due to LMWH – anecdotal<br />

– Potential reversal agent for most of the newer<br />

anticoagulant agents?<br />

• Reports of efficacy are derived from lab<br />

experiments or from healthy volunteers<br />

– Reversal of warfarin<br />

– Reversal of hirudin<br />

– Reversal of fondaparinux<br />

• Recommendations will require clinical data

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