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Coagulation Made Simple

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Evaluation of Excessive Intraoperative<br />

or Postoperative Bleeding<br />

• Previously undetected hemostatic defect<br />

– Congenital defects<br />

• Factor deficiencies<br />

– VIII (Hemophilia A, and/or von Willebrand’s disease)<br />

– IX (Hemophilia B or Christmas disease)<br />

– XI (Hemophilia C)<br />

– II, V, and X<br />

– VII<br />

– XIII<br />

– Transfusion purpura<br />

• Antibodies to donor platelets, which eventually destroy the<br />

host’s own platelets

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