Coagulation Made Simple
Coagulation Made Simple
Coagulation Made Simple
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Evaluation of Excessive Intraoperative<br />
or Postoperative Bleeding<br />
• Previously undetected hemostatic defect<br />
– Congenital defects<br />
• Factor deficiencies<br />
– VIII (Hemophilia A, and/or von Willebrand’s disease)<br />
– IX (Hemophilia B or Christmas disease)<br />
– XI (Hemophilia C)<br />
– II, V, and X<br />
– VII<br />
– XIII<br />
– Transfusion purpura<br />
• Antibodies to donor platelets, which eventually destroy the<br />
host’s own platelets