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Types of mutations and their impact on protein function Today's ...

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Most eukaryotic genes c<strong>on</strong>tain intr<strong>on</strong>s, which are<br />

removed by a process called splicing<br />

The “mature” mRNA has an added 5’ cap <str<strong>on</strong>g>and</str<strong>on</strong>g> poly-A tail,<br />

<str<strong>on</strong>g>and</str<strong>on</strong>g> all <str<strong>on</strong>g>of</str<strong>on</strong>g> the intr<strong>on</strong>s removed. It can be MUCH smaller<br />

than the “primary transcript.”<br />

note: not to scale!<br />

14

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