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A Revolution in R&D

A Revolution in R&D

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CASE STUDY: REDESIGNING R&D GOVERNANCE<br />

A large drug company recently completed an <strong>in</strong>tensive<br />

three-month project to redesign discovery governance<br />

and is already reap<strong>in</strong>g the benefits. The<br />

company had always placed a high value on the<br />

quality of its scientists and their entrepreneurial<br />

drive. Now, however, it was grow<strong>in</strong>g <strong>in</strong>creas<strong>in</strong>gly dissatisfied<br />

with its exist<strong>in</strong>g system of allocat<strong>in</strong>g<br />

resources: the decision-mak<strong>in</strong>g procedures were<br />

prov<strong>in</strong>g very troublesome to navigate, decision makers<br />

were difficult to identify, communication was<br />

poor, and the decisions themselves often seemed<br />

politically motivated rather than guided by scientific<br />

and commercial promise.<br />

In redesign<strong>in</strong>g the decision-mak<strong>in</strong>g procedures, the<br />

company began with a thorough review of its current<br />

governance process, both as espoused and as practiced<br />

(the two were remarkably dist<strong>in</strong>ct <strong>in</strong> certa<strong>in</strong><br />

<strong>in</strong>stances). Various root causes of undesirable outcomes<br />

were identified: these <strong>in</strong>cluded perverse<br />

<strong>in</strong>centives (that is, <strong>in</strong>centives encourag<strong>in</strong>g behavior<br />

Manag<strong>in</strong>g Organizational Change<br />

With the advent of genomics, R&D personnel suddenly<br />

f<strong>in</strong>d themselves <strong>in</strong> alien territory. As the scientific<br />

methods change, the old <strong>in</strong>st<strong>in</strong>ctive<br />

approaches and behaviors need to change as well.<br />

Among the greatest challenges fac<strong>in</strong>g R&D executives<br />

is manag<strong>in</strong>g the human side of change.<br />

How the Scientist’s Job is Chang<strong>in</strong>g<br />

R&D science is shift<strong>in</strong>g from an arena of experimentation<br />

to one <strong>in</strong>creas<strong>in</strong>gly concerned with theoretical<br />

biology. The challenge is now less how to<br />

get the data than what to do with the data collected.<br />

Scientists who formerly could do their jobs virtually<br />

on their own—conduct their own experiments, and<br />

generate and analyze the data themselves—now<br />

f<strong>in</strong>d they need to collaborate with others who have<br />

more specialized technological skills, <strong>in</strong> areas such<br />

as <strong>in</strong>formatics, robotics, or microfabrication.<br />

Indeed, the scientists of the pre-genomics era are<br />

dest<strong>in</strong>ed to evolve <strong>in</strong>to two k<strong>in</strong>ds of successors:<br />

at odds with company strategy); unclear criteria,<br />

which project champions were dis<strong>in</strong>cl<strong>in</strong>ed to clarify,<br />

let alone follow; and <strong>in</strong>adequate allocation of decision<br />

rights (that is, too vague a def<strong>in</strong>ition of who was<br />

entitled to make which decisions), which often<br />

meant that no decision was made at all.<br />

From the lessons learned, a new governance process<br />

was devised. Not just devised, but activated: by<br />

modify<strong>in</strong>g <strong>in</strong>centives, the company ensured that<br />

practice was now properly aligned with espousal.<br />

The new process is work<strong>in</strong>g well: R&D managers<br />

navigate it easily, and decisions are be<strong>in</strong>g made and<br />

communicated clearly and consistently. It allows scientists<br />

more time to focus on their projects, and it<br />

gives those projects appropriate fund<strong>in</strong>g and management<br />

<strong>in</strong>volvement. It has accord<strong>in</strong>gly won the<br />

confidence of those affected by it, and can claim a<br />

considerable contribution to the marked improvement<br />

<strong>in</strong> productivity that has followed its adoption.<br />

those who <strong>in</strong>terpret the data and devise plans for<br />

exploit<strong>in</strong>g it, and those who cont<strong>in</strong>ue to develop<br />

and optimize the technologies required for generat<strong>in</strong>g<br />

the data. (Companies should be sure to recognize<br />

and reward the latter group for its contributions,<br />

and not relegate it to second-class status.)<br />

All scientists will need to become comfortable with<br />

new ways of work<strong>in</strong>g together—more shar<strong>in</strong>g or collectivist<br />

now, less conducive to solitary <strong>in</strong>itiative.<br />

The scientists of the future will still take responsibility<br />

for their own work, but perhaps will no longer<br />

take the credit for it: that will be ascribed to team<br />

effort.<br />

Manag<strong>in</strong>g the Transition<br />

Chang<strong>in</strong>g from bench-based to <strong>in</strong>formation-based<br />

work <strong>in</strong> this way, and from favor<strong>in</strong>g fairly <strong>in</strong>dependent<br />

endeavors to promot<strong>in</strong>g a more collaborative<br />

ethos, is bound to be awkward or even pa<strong>in</strong>ful for<br />

most of those <strong>in</strong>volved, scientists and managers alike.<br />

55

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