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A Revolution in R&D

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Table of Contents<br />

ABOUT THE AUTHORS 4<br />

FOREWORD 5<br />

EXECUTIVE SUMMARY 6<br />

INTRODUCTION 9<br />

CHAPTER 1: THE IMPACT OF GENOMICS 11<br />

Preface 11<br />

The Opportunities 12<br />

The Challenges 18<br />

A F<strong>in</strong>al Word 21<br />

CHAPTER 2: THE IMPACT OF GENETICS 24<br />

Preface 24<br />

Disease Genetics 27<br />

Pharmacogenetics 33<br />

A F<strong>in</strong>al Word 39<br />

CHAPTER 3: MANAGERIAL CHALLENGES 41<br />

Preface: Look<strong>in</strong>g Back and Look<strong>in</strong>g Forward 41<br />

Strategy—Search<strong>in</strong>g for Genomic Competitive Advantage 41<br />

Putt<strong>in</strong>g the Strategy <strong>in</strong>to Operation 49<br />

A F<strong>in</strong>al Word 56<br />

CONCLUSION 57<br />

METHODOLOGY 59<br />

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