Cancer Research - Europa

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Slijper, Monique 120 Sliwka, Ireneusz 107 Smedegaard, Niels 202 Smith, Desmond 149 Smith, Edvard 159 Smith, Graeme 29 Smith, Victoria 221 Sockalingum, Ganesh 118 Sokoloff, Pierre 82 Sonneveld, Pieter 56 Sotiriou, Christos 223 Spaink, Herman P. 248 Spanel, Patrick 107 Spatz, Alan 178 Speicher, Michael 120 Speleman, Frank 128 Splendiani, Andrea 183 Spolders, H. 115 Spyratos, Frédérique 122 Stanislawski, Thomas 59 Stassen, Jean-Marie 165 Stauber, Roland 18 Stauss, Hans 169 Steegmann, J. 198 Steingrimsson, Eirikur 96 Steinkasserer, Alexander 182 Stenman, Ulf-Hakan 147 Stevens, Gary 52 Stieber, Petra 149 Stierum, Rob 90 Stoeber, Kai 52 Stoppelli, Maria Patrizia 115 Storm, Hans 101 Storme, Guy 159 Strand, Ulf 136 Strasser, Florian 235 Stratford, Ian 204 Stroud, Robert 214 Stuart Naylor 169 Stubenrauch, Frank 94 Stunnenberg, Henk 35 Suerbaum, Sebastian 94 Suter, Mark 183 Sutter, Gerd 221 Svensson, Roger 110 Swain, Paul 143 Sweep, Fred C.G.J. 122 Sykova, Eva 14 262 Szendröi, Miklös 37 Taieb, Julien 132 Taipale, Jussi 69 Takalo, Harri 147 Tanke, Hans 120 Taraboletti, Giulia 115 Tartour, Eric 176 Tatusyan, Alexander 192 Tavernarakis, Nektarios 81 Tavitian, Bertrand 115, 192 Taylor, Naomi 169 Te Riele, Hein 59 ten Dijke, Peter 14, 18, 84 Testi, Roberto 81 Teti, Anna Maria 50 Thaler, J. 198 Thalmann, George 67, 152 Theillet, Charles 145 Theobald, Matthias 59 Thieblemont, Catherine 202 Thieffry, Denis 27 Thiel, Andreas 183 Thielemans, Kris 176, 183 Thierry, Dominique 206 Thiéry, Jean-Paul 18 Thomas, Géraldine A. 223 Thomson, Alistair 224 Thomssen, Christoph 223 Thorel, Alain 61 Thoresen, Steinar 233 Thybo, Tanja 20 Tijhuis, Johan 67 Tinsley, Jon 39 Tjonneland, Anne 99, 101 Tobler, A. 198 Tomlinson, Ian 78 Tommasino, Massimo 94 Tönisson, Neeme 59 Toth, Geza 241 Totterman, Thomas 208 Tourwe, Dirk 241 Trapman, Jan 67 Treussart, François 61 Trichopoulos, Dimitrios 237 Trichopoulou, Antonia 99, 101 Trnény, Marek 202 Troussard, X. 199 Trumpp, Andreas 44 Tryggvason, Karl 14, 115 Tschopp, Jurg 210 Tschurtschenthaler, Gertraud 200 Tumino, Rosario 99 Tursz, Thomas 237 Uggeri, Fulvio 192 Ugorski, Maciej 50 Uguccioni, Mariagrazia 183 Uhl, Rainer 120 Ulbrich, Karel 208 Ullmann, A. 198 Umaña, Pablo 156 Unterkofler, Karl 107 Urban, Gerald 204 Vainchenker, William 200 Vajkoczy, Peter 14, 16, 156, 212 Valdes Olmos, Renato A. 103 Valencia, Alfonso 22, 27 Valoti, Massimo 189 van ’t Veer, Laura 120, 224 van Bokhoven, Hans 33 Van Cutsem, Eric 165 van Dam, Hans 31 van den Oord, Joost 178 van der Burght, Roeland 136 van der Kogel, Albert 110 van der Linden, Annemie 192 van der Pluijm, Gabri 50, 67, 152 van Dongen, Guus 156 van Dongen, J. 202 van Engen, Ruben 136 van Gorp, Toon 145 van Huffel, Sabine 130 van Krieken, Johannes H.J.M. 202 van Lohuizen, Maarten 44 van Oers, Monique M 171, 199 Van Roy, Frans 18 Van Valen, Frans 154 van Weerden, Wytske 208 Vandenabeele, Peter 33 Vanderkerken, Karin 56 Vannucchi, Alessandro M. 200 Vasquez, Jose 224 Vassal, Gilles 46 Vendrell, Jean-Pierre 120 Venkitaraman, Ashok 20 Verfaille, Christine 110 Vergote, Ignace B. 145 CANCER RESEARCH PROJECTS FUNDED UNDER THE SIXTH FRAMEWORK PROGRAMME
Vernos, Isabelle 22 Veronesi, Umberto 63 Vert, Jean-Philippe 245 Verweij, Jaap 25 Viale, Giuseppe 223 Vikkula, Miikka 48 Villadsen, Jan 204 Vilo, Jaak 117 Vineis, Paolo 99 Visakorpi, Tapio 67 Visani, Luigi 130 Viscoli, C. 200 Vitti, Francisca 156 Vladareanu, Ana-Maria 200 Voinnet, Olivier 74 von Kries, Jens 141 von Minckwitz, Gunter 223 Voudsen, Karen 12, 44 Wade, Rebecca 214 Wagner, Ernst 208 Wagner, Hermann 183 Walewski, Jan 199, 202 Waligorski, Michael 216 Walisiewicz-Niedbalska, Wieslawa 241 Walker, Anthony 195 Wallis, Matthew 136 Waltenberger, Johannes 14 Ward, K. 200 Wareham, Nick 99 Wassenegger, Michael 74 Wasylyk, Bohdan 67 Weber, Simone 193 Weber, Viktoria 145 Weigel, Detlef 74 Weinberger, Klaus 117 Weiss, Dieter G. 241 Weltmann, Klaus-Dieter 149 Wenger, Roland 204 Wermer, Frank 223 West, Stephen 29 Wester, Hans-Jürgen 193 Wex, Kerstin 107 Wiig, Helge 14 Wijfjes, Andre 92 Willems, Luc 94 Willemze, R. 198 Williger, Ben-Tsion 50 Wiman, Klas 33, 59 INDICES Wingender, Edgar 22 Winther, Henrik 31 Witkovsky, Viktor 107 Wodak, Shoshana 22 Wölfel, Thomas 176 Wolfhard, Semmler 130 Wondergem, Jan 206 Workman, Paul 65 Wouters, Brad 204 Wuyts, Wim 37 Yahioglu, Gokhan 212 Yarden, Yosef 159 Ye, Shu 115 Yiotakis, Athanasios 115 Ylä-Herttuala, Seppo 48 Yoram Reiter 169 Young, Antony 92 Young, Kenneth 136 Young, Lawrence 94 Zaffaroni, Nadia 25, 54 Zalud, Petra 152 Zanda, Matteo 156 Zardi, Luciano 156, 212 Zaritskey, A. 200 Zatloukal, Kurt 245 Zatonski, Witold 101 Zeillinger, Robert 145 Zelig, Eshhar 169 Zhivotovsky, Boris 65 Ziegler, Sibylle 103 Zini, G. 198 Zitvogel, Laurence 183 Zoetelief, Johannes 216 Zollo, Massimo 18, 128 Zvonimir, Rudolph 25 Zwacka, Ralf 226 Zwerschke, Werner 94 Zwierzina, H. 200 263
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PROJECT SYNOPSES CANCER RESEARCH PR
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CANCER RESEARCH PROJECTS FUNDED UND
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TABLE OF CONTENTS FOREWORD - CANCER
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Prevention 97 EPIC 98 EUROCADET 100
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CANCER: COMBATING A COMPLEX DISEASE
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Biology Cancer is a disease ethat t
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p53 activators ASPP Partner 5 NFkap
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Keywords | Angiogenesis | vasculoge
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Keywords | Tumour-host interactions
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Keywords | Breast | metastasis | ge
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Keywords | Identifi cation of novel
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Keywords | Systems biology | modell
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Keywords | Oncology | anticancer th
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• public health research coupled
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Expected results We will construct
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Potential applications Our DNA is u
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Microscopic examination of tissue s
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Pluripotent embryonic stem cells ar
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• Decryption of the leukaemia cel
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• identifi cation of molecular ta
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A B C LT-HSC CSC The Cancer Stem Ce
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X-ray diff raction of target drug c
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using pathway-specifi c reporter ce
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Keywords | Kinases | pediatric panc
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Keywords | Lymphangiogenesis | angi
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Keywords | Breast cancer | metastas
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Keywords | Mitosis | phosphorylatio
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Keywords | Therapy | genome | telom
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Keywords | Multiple myeloma | cance
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Keywords | p53 tumour suppressor |
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Development of eff ective anti-canc
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Coordinator Patrick A. Curmi INSERM
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Drosophila as a model system for tu
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Normal cell growth and epithelial l
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effi ciently with cancer cell proli
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A high-throughput assay of transcri
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Coordinator Ewa Sikora Nencki Insti
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Expected results The SIROCCO consor
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Keywords | Epigenetics | gene regul
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Keywords | Hereditary | tricarboxyl
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Keywords | HSV-1 | hepatocellular c
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Keywords | Apoptosis | autophagy |
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Keywords | Tumour | host | signalli
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Aetiology The uncontrolled cell gro
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Coordinator Rosalind Eeles Reader i
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The parallelogram approach in CARCI
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Keywords | Melanoma | genetics | na
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Keywords | Virus | bacteria | HPV |
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Keywords | Breast | prostate | gene
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Prevention The fact that preventing
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Coordinator Elio Riboli Imperial Co
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Coordinator Jan Willem Coebergh Joh
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Coordinator Jose M a Benlloch Conse
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BAMOD Breath-Gas Analysis for Molec
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BioCare Molecular Imaging for Biolo
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These centres of excellence will in
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Expected results Optimise the benef
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114 Cell proliferation and apoptosi
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COBRED Colon and Breast cancer Diag
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DASIM Diagnostic Applications of Sy
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Expected results Primarily, the res
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Coordinator John A. Foekens Dept. o
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124 Aim Drop-Top has two major obje
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Coordinator Gorka Ochoa Progenika B
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Expected results The E.E.T.-Pipelin
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e developed by eTUMOUR is likely to
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Coordinator Angel Porgador Ben-Guri
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• the design of a compact assembl
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Potential applications We believe t
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Tumor initiation, progression to ma
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MolDiag-Paca Novel Molecular Diagno
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NEMO Nano based capsule-Endoscopy w
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OVCAD Ovarian Cancer - Diagnosis of
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P-MARK Validation of recently devel
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POC4life Multiparametric quantum do
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PROMET Prostate cancer molecular-or
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Micrometastasis in the bone marrow.
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and pharmaco-kinetics studies. This
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Coordinator Raffaella Giavazzi Isti
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• Development of tools for diagno
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Treatment Two major problems when t
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Coordinator Lluis M. Mir UMR 8121 C
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Potential applications ANGIOSTOP ha
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Green-fl uorescence protein- expres
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Coordinator Robert Hawkins Universi
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Expected results The BACULOGENES pr
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descriptors of the molecules to be
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Keywords | Therapeutic vaccine | im
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Keywords | Cancer chemotherapy | dr
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Keywords | Children | cancer | leuk
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Chimaeric TCR shown in context of n
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Andrea Splendiani Leaf Bioscience s
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Coordinator Anne O’Garra The Medi
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Coordinator Jacques Bartholeyns IDM
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Structure Driven Drug Design The in
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• acquire fundamental knowledge a
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Terry Jones Victoria University of
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Potential applications The use of t
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groups and management structures. T
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T. Barbui Azienda Ospedaliera-Osped
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Keywords | Mantle cell lymphoma | t
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Keywords | Hypoxia | HIF | pericell
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Keywords | Radiation-induced compli
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Keywords | Gene therapy | adenoviru
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Keywords | Dependence receptors | a
Page 213 and 214: Keywords | Photodynamic therapy | a
Page 215 and 216: Keywords | Ovarian cancer | thymidy
Page 217 and 218: Keywords | Quality assurance | clin
Page 219 and 220: Keywords | Circadian | clocks | cel
Page 221 and 222: Keywords | Anticancer therapy | onc
Page 223 and 224: Coordinator Monika Lusky Transgene
Page 225 and 226: 6 000 women over a three-year perio
Page 227 and 228: Keywords | Solid tumours | apoptosi
Page 229 and 230: Keywords | Lymphoma | leukaemia | v
Page 231: Coordinator Riccardo Dolcetti Centr
Page 234 and 235: CCPRB Cancer Control using Populati
Page 236 and 237: EPCRC The European Palliative Care
Page 238 and 239: EUROCAN+PLUS Feasibility Study for
Page 240 and 241: EUSTIR A European strategy for the
Page 242 and 243: NORMOLIFE Development of new therap
Page 245 and 246: Scientifi c Model Systems The compl
Page 247 and 248: Performance of benchmarking exercis
Page 249 and 250: • markers correlating with the im
Page 251 and 252: Indices - Keywords Indices - Partne
Page 253 and 254: ● disease markers 131 ● DNA dam
Page 255 and 256: ● renal 77 ● replication 219
Page 257 and 258: Bos, Nico A. 56 Boskovic, Darinka 2
Page 259 and 260: Geley, Stephan 159 Georgopoulos, Li
Page 261 and 262: Lingner, Joachim 54 Linial, Michal
Page 263: Ragno, Pia 115 Rainford, Martyn 92
Page 267 and 268: ● Centre Hospitalier Universitair
Page 269 and 270: ● IFOM - Fondazione Istituto FIRC
Page 271 and 272: ● National University of Ireland
Page 273 and 274: ● University of Bari 174 ● Univ
Page 275 and 276: HOW TO OBTAIN EU PUBLICATIONS Our p
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