Cancer Research - Europa

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Jacobsen, Sten Eirik W. 39 Jalkanen, Markku 48 Jalonen, Harry 221 Janoki, Gyözö 192 Janos Szollosi 169 Januszewicz, Andrzej 78 Jasmin, Didi 156 Jassem, Jacek 224 Jedrzejczak, W. 199 Jelezko, Fedor 61 Jellum, Egil 233 Jennings, Paul 90 Jensen, Sanne 20 Jiang, Wen 165 Jiricny, Josef 29 Jobst, Gerhard 204 Jochemsen, Aart Gerrit 12 Johanness, Ludger 176 Johannsen, Bernd 110 Johansson, B. 199 Johnsen, Hans E. 56 Jonassen, Inge 14 Jones, Jonathan 81 Jones, Terry 193 Joore, Jos 37 Jotereau, Francine 195 Jotterand, M. 198 Judson, Ian 25 Juntunen, Mikko 136 Kaaks, Rudolf 99 Kaasa, Stein 235 Kacsuk, Peter 174 Kadouche, Jean 112 Kafrouni, Hanna 216 Kalén, Mattias 48 Kalland, Karl-Henning 14 Kallioniemi, Olli 31, 35, 67, 115 Kälvesten, Edvard 136 Kanopka, Arvydas 204 Kanz, L. 200 Karssemeijer, Nico 136 Katz, Emil 143 Kaufman, Marcelline 22 Keidiing, Susanne 110 Keilholz, Ulrich 176 Keller, Jutta 143 Kéri, György 41, 44, 94 Kerjaschki, Dontscho 48 258 Kerr, David 237 Ketting, René 74 Keun, Hector 90 Key, Timothy 99 Kiemeney, L.A.L.M. 96 Kiessling, Rolf 183, 195 Kimchi, Adi 81 Kindblom, Lars-Gunnar 37 Kjems, Jørgen 74 Klaassen, Arno 130 Klapper, Wolfram 202 Klein, Bernhard 56 Klein, Christoph 138 Kleinjans, Jos 90 Klener, P. 200 Klepp, Knut-Inge 101 Kless, Hader 126 Klöppel, G. 141 Kluin, Philip M. 202 Kneba, M. 199 Knoblich, Jürgen 63 Knox, Susan 224 Knuutila, Sakari 37, 154, 199 Koch, Troels 46 Kochanek, Stefan 208 Koenig, Jochen 90, 94 Koensgen, Dominique 145 Kolch, Walter 41 Kombi, David 171 Kos, Janko 115 Koskela, Pentti 233 Kosmehl, Hartwig 156 Koubi, David 221 Kousparou, Christina 212 Kouzarides, Tony 35, 76 Kovar, Heinrich 128, 154 Kreipe, H. 198 Kreisler, Peter 130 Krivan, G. 199 Kroemer, Guido 12, 81, 178 Krokan, Hans 29 Krueger, Anke 61 Krug, Alfons 204 Krüger, Achim 115 Kruger-Kjaer, Susanne 94 Kubbutat, Michael 14 Kunst, A. 101 Kury, Fritz 145 Kyewski, Bruno 176 La Thangue, Nicholas B. 12 Labar, B. 199 Labigne, Agnès 94 Lacal, Juan Carlos 65 Lacombe, Denis 223 Lah Turnsek, Tamara 115 Laidler, Piotr 195 Lain, Sonia 12 Lambin, Phillippe 110, 204 Landegren, Ulf 31 Lane, David 12 Lange, Peter 237 Langedijk, Maria 229 Langer, Thierry 20 Lanvers-kaminsky, Claudia 46 Lanzavechia, Antonio 183 Lapôtre, Laurence 181 Larson, Sten 216 Larsson, Anders 31 Lavielle, Solange 61 Le Bousse-Kerdilès, M. 199 Leachman, Sancy 92 Leal da Silva, Jose Manuel 224 Lecesne, Axel 25 Leconte, Agnès 154 Lefkopoulos, Dimitri 216 Legastellois, Stéphane 61 Lehmann, Alan 29 Lehrach, Hans 245 Lehtinen, Matti 233 Leifland, Karin 136 Lemoine, Nicholas 141 Lenner, Per 233 Leonard, Robert C.F. 223 Leroux, Thierry 216 Lévi, Francis 218 Levitzki, A. 200 Levrero, Massimo 12 Lichinister, Mikhail 224 Lidereau, Rosette 50 Lilige, Hans 147 Lillington, D. 199 Linardopoulos, Spiros 65 Lindahl, Per 48 Lindberg Møller, Birger 20 Lindholm, Leif 208 Line, Aija 195 CANCER RESEARCH PROJECTS FUNDED UNDER THE SIXTH FRAMEWORK PROGRAMME
Lingner, Joachim 54 Linial, Michal 27 Link, H. 200 Linseisen, Jakob 99 Lion, Thomas 199, 200 Lipkowska, Zofia 241 Lipkowski, Andrzej W. 241 List, Heinz Jochim 143 Little, Melvyn 16 Ljungmann, P. 198 Llombart-Bosch, Antonio 37, 154 Lluch, Magí 130 Locasciulli, A. 200 Lock, Edward 90 Löf, Johan 110 Löhmannsröben, Hans-Gerd 149 Loiseau, Alexandre 192 Lombardi, Paolo 214 Lopez-Otin, Carlos 115 Lorenzi, Luca 33 Loskog, Angelica 167 Löve, Arthur 233 Lowik, Clemens 192 Lowndes, Noel 29 Lu, Xin 12 Lubinski, Jan 69, 87, 92 Ludwig, W. 199 Lui, Alberto 143 Lukanidin, Eugene 18 Lukes, Ivan 192 Luleci, Guven 87 Lund, Eiliv 99 Lundeberg, Joakim 178 Luppi, Mario 94 Lusky, Monika 221 Lyng, Fiona 118 Lzaurralde, Elisa 74 Ma Benlloch, Jose 103 Mach, Jean-Pierre 112 Machado, Jose 94 Macino, Giuseppe 74 Mackenbach, Johan 101 Mackensen, Andreas 187 MacPherson, Gordon G. 182 Madsen, Lise 20 Maecke, Helmut 192 Maggi, Adriana 35, 192 Mahon, F. 198 INDICES Mähönen, Anssi 171 Maier, Sabine 122 Mainil, Pierre 37 Maitland, Norman James 67, 208 Malandain, Grégoire 216 Malats, Nuria 126, 141 Malka, David 117 Malvy, Claude 154 Mandelboim, Ofer 16 Mann, Graham 92 Mann, John 54 Mann, Matthias 183 Manservigi, Roberto 80 Mansmann, U. 198 Mantovani, Alberto 169, 183 Mantovani, Roberto 12, 33 Manz, Markus 183 Marcelli, Augusto 118 Marczin, Nandor 107 Margesin, Rosa 107 Margison, Geoff 178 Marie, J. 198 Markopoulos, Christos 223 Marsoni, Silvia 156 Martens, John W.M. 122 Martens, Uwe 54 Martiat, P. 200 Martin, Michèle 206 Martinez, Carmen 99 Martinez-Climent, Jose Angel 202 Martin-Moreno, Jose Martin 237 Martinou, Jean-Claude 65 Martinsson-Niskanen, Titti 165 Marty, Michel 25 Masszi, T. 200 Masucci, Maria 94, 229 Matutes, E. 199 Mavromara, Penelope 80 Maxwell, Patrick 204 Mayer, Bernd 145 Mayer, J. 198 McGrath, John 33 Mecucci, C. 199 Medico, Enzo 159 Megraud, Francis 94 Mehlen, Patrick 210 Meijer, Annemarie H. 248 Meijer, Laurent 218 Meister, Gunter 74 Meitinger, Thomas 202 Melief, C.J.M. 183 Melief, Cornelis 176 Melino, Gerry 12, 33 Mellstedt, Hakan 183 Merbach, André E. 192 Mercey, T. 115 Mergny, Jean-Louis 54 Merten, Otto-Wilhelm 171 Mertens, Fredrik 37 Meyer, Thomas 74, 94 Micheli, Andrea 101 Middleton, Mark 178 Migneco, Emilio 216 Miklavcic, Damijan 163 Miller, Crispin 245 Mills, John 216 Mills, K. 200 Mink, Mátyás 248 Minn, Heikki 110 Minucci, Saverio 35, 174 Mir, Lluis M. 163 Mischak, Harald 94 Misicka-Kesik, Aleksandra 241 Miska, Eric 74 Mittelman, M. 200 Molina, Rafael 149 Mondiano, Anna 169 Montoya, Guillermo 226 Montserrat, E. 198 Mooï, Wolter 82 Moresco, Rosa Maria 193 Moser, Muriel 176, 182, 185 Mosialos, George 94 Moss, David 118 Moszynski, Marek 110 Mouridsen, Henning 223 Mouritzen, Peter 74 Mueller, Margareta M. 115 Mufti, G. 199 Mullenders, Leon 29, 90 Muller, Robert 192 Mundy, John 81 Murphy, Gillian 115 Mürtz, Manfred 107 Musacchio, Andrea 52 Mustea, Alexander 145 259
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PROJECT SYNOPSES CANCER RESEARCH PR
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CANCER RESEARCH PROJECTS FUNDED UND
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TABLE OF CONTENTS FOREWORD - CANCER
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Prevention 97 EPIC 98 EUROCADET 100
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CANCER: COMBATING A COMPLEX DISEASE
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Biology Cancer is a disease ethat t
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p53 activators ASPP Partner 5 NFkap
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Keywords | Angiogenesis | vasculoge
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Keywords | Tumour-host interactions
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Keywords | Breast | metastasis | ge
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Keywords | Identifi cation of novel
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Keywords | Systems biology | modell
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Keywords | Oncology | anticancer th
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• public health research coupled
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Expected results We will construct
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Potential applications Our DNA is u
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Microscopic examination of tissue s
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Pluripotent embryonic stem cells ar
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• Decryption of the leukaemia cel
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• identifi cation of molecular ta
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A B C LT-HSC CSC The Cancer Stem Ce
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X-ray diff raction of target drug c
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using pathway-specifi c reporter ce
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Keywords | Kinases | pediatric panc
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Keywords | Lymphangiogenesis | angi
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Keywords | Breast cancer | metastas
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Keywords | Mitosis | phosphorylatio
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Keywords | Therapy | genome | telom
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Keywords | Multiple myeloma | cance
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Keywords | p53 tumour suppressor |
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Development of eff ective anti-canc
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Coordinator Patrick A. Curmi INSERM
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Drosophila as a model system for tu
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Normal cell growth and epithelial l
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effi ciently with cancer cell proli
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A high-throughput assay of transcri
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Coordinator Ewa Sikora Nencki Insti
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Expected results The SIROCCO consor
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Keywords | Epigenetics | gene regul
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Keywords | Hereditary | tricarboxyl
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Keywords | HSV-1 | hepatocellular c
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Keywords | Apoptosis | autophagy |
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Keywords | Tumour | host | signalli
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Aetiology The uncontrolled cell gro
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Coordinator Rosalind Eeles Reader i
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The parallelogram approach in CARCI
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Keywords | Melanoma | genetics | na
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Keywords | Virus | bacteria | HPV |
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Keywords | Breast | prostate | gene
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Prevention The fact that preventing
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Coordinator Elio Riboli Imperial Co
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Coordinator Jan Willem Coebergh Joh
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Coordinator Jose M a Benlloch Conse
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BAMOD Breath-Gas Analysis for Molec
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BioCare Molecular Imaging for Biolo
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These centres of excellence will in
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Expected results Optimise the benef
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114 Cell proliferation and apoptosi
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COBRED Colon and Breast cancer Diag
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DASIM Diagnostic Applications of Sy
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Expected results Primarily, the res
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Coordinator John A. Foekens Dept. o
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124 Aim Drop-Top has two major obje
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Coordinator Gorka Ochoa Progenika B
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Expected results The E.E.T.-Pipelin
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e developed by eTUMOUR is likely to
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Coordinator Angel Porgador Ben-Guri
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• the design of a compact assembl
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Potential applications We believe t
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Tumor initiation, progression to ma
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MolDiag-Paca Novel Molecular Diagno
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NEMO Nano based capsule-Endoscopy w
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OVCAD Ovarian Cancer - Diagnosis of
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P-MARK Validation of recently devel
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POC4life Multiparametric quantum do
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PROMET Prostate cancer molecular-or
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Micrometastasis in the bone marrow.
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and pharmaco-kinetics studies. This
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Coordinator Raffaella Giavazzi Isti
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• Development of tools for diagno
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Treatment Two major problems when t
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Coordinator Lluis M. Mir UMR 8121 C
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Potential applications ANGIOSTOP ha
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Green-fl uorescence protein- expres
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Coordinator Robert Hawkins Universi
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Expected results The BACULOGENES pr
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descriptors of the molecules to be
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Keywords | Therapeutic vaccine | im
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Keywords | Cancer chemotherapy | dr
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Keywords | Children | cancer | leuk
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Chimaeric TCR shown in context of n
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Andrea Splendiani Leaf Bioscience s
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Coordinator Anne O’Garra The Medi
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Coordinator Jacques Bartholeyns IDM
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Structure Driven Drug Design The in
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• acquire fundamental knowledge a
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Terry Jones Victoria University of
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Potential applications The use of t
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groups and management structures. T
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T. Barbui Azienda Ospedaliera-Osped
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Keywords | Mantle cell lymphoma | t
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Keywords | Hypoxia | HIF | pericell
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Keywords | Radiation-induced compli
Page 209 and 210: Keywords | Gene therapy | adenoviru
Page 211 and 212: Keywords | Dependence receptors | a
Page 213 and 214: Keywords | Photodynamic therapy | a
Page 215 and 216: Keywords | Ovarian cancer | thymidy
Page 217 and 218: Keywords | Quality assurance | clin
Page 219 and 220: Keywords | Circadian | clocks | cel
Page 221 and 222: Keywords | Anticancer therapy | onc
Page 223 and 224: Coordinator Monika Lusky Transgene
Page 225 and 226: 6 000 women over a three-year perio
Page 227 and 228: Keywords | Solid tumours | apoptosi
Page 229 and 230: Keywords | Lymphoma | leukaemia | v
Page 231: Coordinator Riccardo Dolcetti Centr
Page 234 and 235: CCPRB Cancer Control using Populati
Page 236 and 237: EPCRC The European Palliative Care
Page 238 and 239: EUROCAN+PLUS Feasibility Study for
Page 240 and 241: EUSTIR A European strategy for the
Page 242 and 243: NORMOLIFE Development of new therap
Page 245 and 246: Scientifi c Model Systems The compl
Page 247 and 248: Performance of benchmarking exercis
Page 249 and 250: • markers correlating with the im
Page 251 and 252: Indices - Keywords Indices - Partne
Page 253 and 254: ● disease markers 131 ● DNA dam
Page 255 and 256: ● renal 77 ● replication 219
Page 257 and 258: Bos, Nico A. 56 Boskovic, Darinka 2
Page 259: Geley, Stephan 159 Georgopoulos, Li
Page 263 and 264: Ragno, Pia 115 Rainford, Martyn 92
Page 265 and 266: Vernos, Isabelle 22 Veronesi, Umber
Page 267 and 268: ● Centre Hospitalier Universitair
Page 269 and 270: ● IFOM - Fondazione Istituto FIRC
Page 271 and 272: ● National University of Ireland
Page 273 and 274: ● University of Bari 174 ● Univ
Page 275 and 276: HOW TO OBTAIN EU PUBLICATIONS Our p
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