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PROJECT SYNOPSES CANCER RESEARCH PR
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CANCER RESEARCH PROJECTS FUNDED UND
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TABLE OF CONTENTS FOREWORD - CANCER
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Prevention 97 EPIC 98 EUROCADET 100
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CANCER: COMBATING A COMPLEX DISEASE
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Biology Cancer is a disease ethat t
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p53 activators ASPP Partner 5 NFkap
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Keywords | Angiogenesis | vasculoge
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Keywords | Tumour-host interactions
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Keywords | Breast | metastasis | ge
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Keywords | Identifi cation of novel
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Keywords | Systems biology | modell
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Keywords | Oncology | anticancer th
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• public health research coupled
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Expected results We will construct
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Potential applications Our DNA is u
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Microscopic examination of tissue s
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Pluripotent embryonic stem cells ar
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• Decryption of the leukaemia cel
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• identifi cation of molecular ta
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A B C LT-HSC CSC The Cancer Stem Ce
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X-ray diff raction of target drug c
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using pathway-specifi c reporter ce
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Keywords | Kinases | pediatric panc
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Keywords | Lymphangiogenesis | angi
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Keywords | Breast cancer | metastas
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Keywords | Mitosis | phosphorylatio
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Keywords | Therapy | genome | telom
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Keywords | Multiple myeloma | cance
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Keywords | p53 tumour suppressor |
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Development of eff ective anti-canc
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Coordinator Patrick A. Curmi INSERM
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Drosophila as a model system for tu
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Normal cell growth and epithelial l
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effi ciently with cancer cell proli
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A high-throughput assay of transcri
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Coordinator Ewa Sikora Nencki Insti
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Expected results The SIROCCO consor
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Keywords | Epigenetics | gene regul
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Keywords | Hereditary | tricarboxyl
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Keywords | HSV-1 | hepatocellular c
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Keywords | Apoptosis | autophagy |
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Keywords | Tumour | host | signalli
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Aetiology The uncontrolled cell gro
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Coordinator Rosalind Eeles Reader i
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The parallelogram approach in CARCI
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Keywords | Melanoma | genetics | na
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Keywords | Virus | bacteria | HPV |
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Keywords | Breast | prostate | gene
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Prevention The fact that preventing
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Coordinator Elio Riboli Imperial Co
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Coordinator Jan Willem Coebergh Joh
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Coordinator Jose M a Benlloch Conse
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BAMOD Breath-Gas Analysis for Molec
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BioCare Molecular Imaging for Biolo
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These centres of excellence will in
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Expected results Optimise the benef
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114 Cell proliferation and apoptosi
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COBRED Colon and Breast cancer Diag
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DASIM Diagnostic Applications of Sy
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Expected results Primarily, the res
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Coordinator John A. Foekens Dept. o
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124 Aim Drop-Top has two major obje
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Coordinator Gorka Ochoa Progenika B
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Expected results The E.E.T.-Pipelin
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e developed by eTUMOUR is likely to
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Coordinator Angel Porgador Ben-Guri
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• the design of a compact assembl
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Potential applications We believe t
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Tumor initiation, progression to ma
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MolDiag-Paca Novel Molecular Diagno
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NEMO Nano based capsule-Endoscopy w
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OVCAD Ovarian Cancer - Diagnosis of
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P-MARK Validation of recently devel
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POC4life Multiparametric quantum do
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PROMET Prostate cancer molecular-or
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Micrometastasis in the bone marrow.
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and pharmaco-kinetics studies. This
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Coordinator Raffaella Giavazzi Isti
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• Development of tools for diagno
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Treatment Two major problems when t
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Coordinator Lluis M. Mir UMR 8121 C
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Potential applications ANGIOSTOP ha
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Green-fl uorescence protein- expres
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Coordinator Robert Hawkins Universi
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Expected results The BACULOGENES pr
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descriptors of the molecules to be
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Keywords | Therapeutic vaccine | im
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Keywords | Cancer chemotherapy | dr
- Page 181 and 182: Keywords | Children | cancer | leuk
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- Page 185 and 186: Andrea Splendiani Leaf Bioscience s
- Page 187 and 188: Coordinator Anne O’Garra The Medi
- Page 189 and 190: Coordinator Jacques Bartholeyns IDM
- Page 191 and 192: Structure Driven Drug Design The in
- Page 193 and 194: • acquire fundamental knowledge a
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- Page 197 and 198: Potential applications The use of t
- Page 199 and 200: groups and management structures. T
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- Page 203 and 204: Keywords | Mantle cell lymphoma | t
- Page 205 and 206: Keywords | Hypoxia | HIF | pericell
- Page 207 and 208: Keywords | Radiation-induced compli
- Page 209 and 210: Keywords | Gene therapy | adenoviru
- Page 211 and 212: Keywords | Dependence receptors | a
- Page 213 and 214: Keywords | Photodynamic therapy | a
- Page 215 and 216: Keywords | Ovarian cancer | thymidy
- Page 217 and 218: Keywords | Quality assurance | clin
- Page 219 and 220: Keywords | Circadian | clocks | cel
- Page 221 and 222: Keywords | Anticancer therapy | onc
- Page 223 and 224: Coordinator Monika Lusky Transgene
- Page 225 and 226: 6 000 women over a three-year perio
- Page 227 and 228: Keywords | Solid tumours | apoptosi
- Page 229 and 230: Keywords | Lymphoma | leukaemia | v
- Page 231: Coordinator Riccardo Dolcetti Centr
- Page 235 and 236: Work in the -80˚ facility in the M
- Page 237 and 238: Identifi cation of profi les of gen
- Page 239 and 240: Expected results The project shall
- Page 241 and 242: Expected results • A European ove
- Page 243: Nerve cells cultured on a micro-ele
- Page 246 and 247: ESBIC-D European Systems Biology In
- Page 248 and 249: ZF-TOOLS High-throughput Tools for
- Page 250 and 251: Coordinator Annemarie H. Meijer Ins
- Page 252 and 253: Indices - Keywords ● accurate pat
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- Page 256 and 257: Indices - Partners Aaltonen, Lauri
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- Page 260 and 261: Jacobsen, Sten Eirik W. 39 Jalkanen
- Page 262 and 263: Myklebost, Ola 37 Myllykallio, Hann
- Page 264 and 265: Slijper, Monique 120 Sliwka, Ireneu
- Page 266 and 267: Indices - Organisations ● Aalborg
- Page 268 and 269: ● Europa Donna - The European Bre
- Page 270 and 271: ● Jules Bordet Institute 200 ●
- Page 272 and 273: ● TargetEx 174 ● Technical Univ
- Page 274 and 275: European Commission Cancer Research
- Page 276: CANCER RESEARCH PROJECTS FUNDED UND