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PROJECT SYNOPSES CANCER RESEARCH PR
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CANCER RESEARCH PROJECTS FUNDED UND
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TABLE OF CONTENTS FOREWORD - CANCER
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Prevention 97 EPIC 98 EUROCADET 100
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CANCER: COMBATING A COMPLEX DISEASE
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Biology Cancer is a disease ethat t
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p53 activators ASPP Partner 5 NFkap
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Keywords | Angiogenesis | vasculoge
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Keywords | Tumour-host interactions
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Keywords | Breast | metastasis | ge
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Keywords | Identifi cation of novel
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Keywords | Systems biology | modell
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Keywords | Oncology | anticancer th
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• public health research coupled
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Expected results We will construct
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Potential applications Our DNA is u
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Microscopic examination of tissue s
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Pluripotent embryonic stem cells ar
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• Decryption of the leukaemia cel
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• identifi cation of molecular ta
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A B C LT-HSC CSC The Cancer Stem Ce
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X-ray diff raction of target drug c
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using pathway-specifi c reporter ce
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Keywords | Kinases | pediatric panc
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Keywords | Lymphangiogenesis | angi
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Keywords | Breast cancer | metastas
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Keywords | Mitosis | phosphorylatio
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Keywords | Therapy | genome | telom
- Page 57 and 58: Keywords | Multiple myeloma | cance
- Page 59 and 60: Keywords | p53 tumour suppressor |
- Page 61 and 62: Development of eff ective anti-canc
- Page 63 and 64: Coordinator Patrick A. Curmi INSERM
- Page 65 and 66: Drosophila as a model system for tu
- Page 67 and 68: Normal cell growth and epithelial l
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- Page 71 and 72: A high-throughput assay of transcri
- Page 73 and 74: Coordinator Ewa Sikora Nencki Insti
- Page 75 and 76: Expected results The SIROCCO consor
- Page 77 and 78: Keywords | Epigenetics | gene regul
- Page 79 and 80: Keywords | Hereditary | tricarboxyl
- Page 81 and 82: Keywords | HSV-1 | hepatocellular c
- Page 83 and 84: Keywords | Apoptosis | autophagy |
- Page 85 and 86: Keywords | Tumour | host | signalli
- Page 87 and 88: Aetiology The uncontrolled cell gro
- Page 89 and 90: Coordinator Rosalind Eeles Reader i
- Page 91 and 92: The parallelogram approach in CARCI
- Page 93 and 94: Keywords | Melanoma | genetics | na
- Page 95 and 96: Keywords | Virus | bacteria | HPV |
- Page 97 and 98: Keywords | Breast | prostate | gene
- Page 99 and 100: Prevention The fact that preventing
- Page 101 and 102: Coordinator Elio Riboli Imperial Co
- Page 103 and 104: Coordinator Jan Willem Coebergh Joh
- Page 105: Coordinator Jose M a Benlloch Conse
- Page 110 and 111: BioCare Molecular Imaging for Biolo
- Page 112 and 113: These centres of excellence will in
- Page 114 and 115: Expected results Optimise the benef
- Page 116 and 117: 114 Cell proliferation and apoptosi
- Page 118 and 119: COBRED Colon and Breast cancer Diag
- Page 120 and 121: DASIM Diagnostic Applications of Sy
- Page 122 and 123: Expected results Primarily, the res
- Page 124 and 125: Coordinator John A. Foekens Dept. o
- Page 126 and 127: 124 Aim Drop-Top has two major obje
- Page 128 and 129: Coordinator Gorka Ochoa Progenika B
- Page 130 and 131: Expected results The E.E.T.-Pipelin
- Page 132 and 133: e developed by eTUMOUR is likely to
- Page 134 and 135: Coordinator Angel Porgador Ben-Guri
- Page 136 and 137: • the design of a compact assembl
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- Page 140 and 141: Tumor initiation, progression to ma
- Page 142 and 143: MolDiag-Paca Novel Molecular Diagno
- Page 144 and 145: NEMO Nano based capsule-Endoscopy w
- Page 146 and 147: OVCAD Ovarian Cancer - Diagnosis of
- Page 148 and 149: P-MARK Validation of recently devel
- Page 150 and 151: POC4life Multiparametric quantum do
- Page 152 and 153: PROMET Prostate cancer molecular-or
- Page 154 and 155: Micrometastasis in the bone marrow.
- Page 156 and 157: and pharmaco-kinetics studies. This
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Coordinator Raffaella Giavazzi Isti
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• Development of tools for diagno
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Treatment Two major problems when t
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Coordinator Lluis M. Mir UMR 8121 C
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Potential applications ANGIOSTOP ha
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Green-fl uorescence protein- expres
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Coordinator Robert Hawkins Universi
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Expected results The BACULOGENES pr
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descriptors of the molecules to be
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Keywords | Therapeutic vaccine | im
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Keywords | Cancer chemotherapy | dr
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Keywords | Children | cancer | leuk
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Chimaeric TCR shown in context of n
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Andrea Splendiani Leaf Bioscience s
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Coordinator Anne O’Garra The Medi
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Coordinator Jacques Bartholeyns IDM
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Structure Driven Drug Design The in
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• acquire fundamental knowledge a
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Terry Jones Victoria University of
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Potential applications The use of t
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groups and management structures. T
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T. Barbui Azienda Ospedaliera-Osped
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Keywords | Mantle cell lymphoma | t
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Keywords | Hypoxia | HIF | pericell
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Keywords | Radiation-induced compli
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Keywords | Gene therapy | adenoviru
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Keywords | Dependence receptors | a
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Keywords | Photodynamic therapy | a
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Keywords | Ovarian cancer | thymidy
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Keywords | Quality assurance | clin
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Keywords | Circadian | clocks | cel
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Keywords | Anticancer therapy | onc
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Coordinator Monika Lusky Transgene
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6 000 women over a three-year perio
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Keywords | Solid tumours | apoptosi
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Keywords | Lymphoma | leukaemia | v
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Coordinator Riccardo Dolcetti Centr
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CCPRB Cancer Control using Populati
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EPCRC The European Palliative Care
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EUROCAN+PLUS Feasibility Study for
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EUSTIR A European strategy for the
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NORMOLIFE Development of new therap
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Scientifi c Model Systems The compl
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Performance of benchmarking exercis
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• markers correlating with the im
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Indices - Keywords Indices - Partne
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● disease markers 131 ● DNA dam
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● renal 77 ● replication 219
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Bos, Nico A. 56 Boskovic, Darinka 2
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Geley, Stephan 159 Georgopoulos, Li
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Lingner, Joachim 54 Linial, Michal
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Ragno, Pia 115 Rainford, Martyn 92
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Vernos, Isabelle 22 Veronesi, Umber
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● Centre Hospitalier Universitair
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● IFOM - Fondazione Istituto FIRC
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● National University of Ireland
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● University of Bari 174 ● Univ
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