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A2 milk ? Fleckvieh reveals another secret!

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22 AUSTRALIA<br />

<strong>A2</strong> <strong>milk</strong> – <strong>Fleckvieh</strong> <strong>reveals</strong> <strong>another</strong> <strong>secret</strong>!<br />

George Cassar, Karova <strong>Fleckvieh</strong>, Australia<br />

Research done in several countries has suggested that there might be a link between the consumption<br />

of A1 <strong>milk</strong> to heart disease, insulin-dependent diabetes and autism. However, these theories are based on<br />

statistical correlations, animal research or anecdotal reports. The fact is that <strong>Fleckvieh</strong> has a high percentage<br />

of <strong>A2</strong> <strong>milk</strong>, which is supposed to be the „good” type. Bavarian <strong>Fleckvieh</strong> Genetics had several of its<br />

bulls tested for their Beta Casein types. Read the results of that testing in the following article.<br />

The composition of <strong>milk</strong><br />

Milk is made up of approximately<br />

85 % water, 4.6 % lactose, 3.7 % fat,<br />

3.3 % protein, 0.5 % minerals and<br />

3 % miscellaneous.<br />

The protein in <strong>milk</strong> is made up of<br />

caseins, whey proteins and enzymes.<br />

The caseins in protein are made<br />

up of 36 % Alpha Casein, 27 %<br />

Beta Casein, 9 % Kappa Casein and<br />

27 % Peptides and amino acids.<br />

Beta casein<br />

In the <strong>milk</strong> of dairy cows there are<br />

two forms or variants of the Beta<br />

Casein protein.<br />

They can be either <strong>A2</strong>, which is considered<br />

to be the original form of<br />

Beta Casein or A1 Beta Casein<br />

which is the modern variant and<br />

believed to have resulted from mutations<br />

and the domestication of<br />

cattle by man. There are also other<br />

variants of both forms of Beta Casein<br />

but they are still divided into<br />

the <strong>A2</strong> and A1 categories. Milk Protein<br />

is made up of chains of many<br />

amino acids and in Beta Casein the<br />

chain is 209 Amino Acids long.<br />

The difference between <strong>A2</strong> and A1<br />

Beta Casein protein is in a single<br />

amino acid at position 67. This amino<br />

acid is called Proline in <strong>A2</strong> <strong>milk</strong><br />

and Histidine in A1 <strong>milk</strong>. Other species<br />

of animals like Goat, Water<br />

Buffalo and Yak, as well as human<br />

breast <strong>milk</strong> all contain the <strong>A2</strong>-like<br />

form of beta casein as they have a<br />

Proline Amino Acid at position 67 in<br />

their beta casein chain.<br />

Histidine amino acid at position 67<br />

makes that Cow's <strong>milk</strong> is unique<br />

amongst all mammals. The Histidine<br />

link is important because betacasein<br />

also contains a chain of amino<br />

acids (peptides) called Beta-Ca-<br />

Beta casein<br />

<strong>A2</strong><br />

The above diagram depicts the modern variants of the original <strong>A2</strong>-type of Beta Casein.<br />

somorphin-7 (BCM-7), which is a<br />

powerful opioid and oxidant and<br />

has been linked to negative health<br />

effects. The Proline that exists in <strong>A2</strong><br />

cows has a strong bond to BCM-7.<br />

The Histidine in A1 <strong>milk</strong> however,<br />

has weak hold on BCM-7, which allows<br />

it to break away from the rest<br />

of the chain and flow freely about in<br />

the <strong>milk</strong>. It should be difficult for<br />

BCM-7 to get through the gut wall<br />

and into the bloodstream because<br />

the molecule is too large. However,<br />

some people suffer from a condition<br />

referred to as leaky gut syndrome<br />

which allows BCM-7 and other<br />

peptides to pass easily through the<br />

gut wall and into the bloodstream.<br />

There is also very strong evidence<br />

that people with stomach ulcers or<br />

untreated coeliac disease can absorb<br />

BCM7 through the gut wall. It<br />

is also possible that babies can absorb<br />

BCM-7 the same way as they<br />

need to be able to pass large molecules<br />

through the gut wall to be able<br />

to absorb the colostrum in their<br />

mother’s <strong>milk</strong>.<br />

A1<br />

A3<br />

E<br />

D<br />

H<br />

B<br />

C<br />

The proponents of <strong>A2</strong> <strong>milk</strong> believe<br />

that exposure to BCM-7 has been<br />

linked to: neurological impairment,<br />

including autism and schizophrenic<br />

changes, type-1 diabetes, an impaired<br />

immune response, autoimmune<br />

disease and heart disease.<br />

Whilst there has not been any conclusive<br />

scientific test done to date<br />

to prove or disprove such evidence,<br />

those using <strong>A2</strong> <strong>milk</strong> are shouting<br />

out it’s praises and there is a growing<br />

awareness amongst today’s<br />

health conscious consumers of the<br />

claimed benefits of drinking <strong>A2</strong><br />

<strong>milk</strong>.<br />

How does <strong>Fleckvieh</strong> compare<br />

regarding the incidence of<br />

the <strong>A2</strong> best casein?<br />

Each animal has a pair of genes for<br />

the beta casein protein and during<br />

fertilization one of these genes is<br />

contributed to the offspring. These<br />

can be either <strong>A2</strong><strong>A2</strong> , A1A1 or a combination<br />

of both genes, A1<strong>A2</strong>. As it<br />

is early days of testing for the <strong>A2</strong><br />

F<br />

G<br />

H<br />

FLECKVIEHWorld 2010/2011


Beta Casein protein, the studies done<br />

to date in 10 countrys and across<br />

7 dairy breeds between 1982 and<br />

2006 show that <strong>Fleckvieh</strong> had the<br />

2nd highest frequency of the <strong>A2</strong> Beta<br />

Casein Protein. Six studies included<br />

Holsteins, three studies included<br />

Jerseys and one study each<br />

one Ayrshire, Guernsey, Brown<br />

Swiss, Milking Shorthorn and <strong>Fleckvieh</strong>.<br />

The <strong>Fleckvieh</strong> study was published<br />

in the Czech Journal of animal<br />

Science in 2006 and was conducted<br />

on 440 animals of the Czech <strong>Fleckvieh</strong><br />

breed. Of the 440 <strong>Fleckvieh</strong> animals<br />

tested:<br />

67 % tested <strong>A2</strong><strong>A2</strong><br />

30 % tested A1<strong>A2</strong><br />

3 % to the A1A1<br />

The opposite graph shows results<br />

on tests done to date to compare<br />

between breeds and from it can be<br />

seen the high incidence of the <strong>A2</strong><br />

Beta Casein gene in <strong>Fleckvieh</strong>.<br />

These results are consistent with<br />

expectations and show a high percentage<br />

of bulls carrying the <strong>A2</strong> Beta<br />

Casein gene, therefore giving<br />

great scope for those wishing to<br />

pursue <strong>A2</strong><strong>A2</strong> breeding within their<br />

herd.<br />

The scientific results obtained to<br />

date are very promising for <strong>Fleckvieh</strong>.<br />

Should the additional health<br />

benefits of <strong>A2</strong> <strong>milk</strong> prove true this<br />

would be <strong>another</strong> big advantage<br />

for <strong>Fleckvieh</strong>.<br />

<strong>A2</strong>-tests on 9 bulls from<br />

Bavarian <strong>Fleckvieh</strong> Genetics<br />

Engadin <strong>A2</strong><strong>A2</strong><br />

Rustico <strong>A2</strong><strong>A2</strong><br />

Waterberg <strong>A2</strong><strong>A2</strong><br />

Seebär <strong>A2</strong><strong>A2</strong><br />

Mandela A1<strong>A2</strong><br />

Don Juan A1<strong>A2</strong><br />

Hippo A1<strong>A2</strong><br />

Round Up A1<strong>A2</strong><br />

Manitoba A1A1<br />

Whilst the author has sourced the above<br />

information from articles and research that<br />

is currently available, the author, nor Bavarian<br />

<strong>Fleckvieh</strong> Genetics endorse any<br />

claims made regarding the benefits or consequence<br />

of drinking A1 or <strong>A2</strong> <strong>milk</strong>. The sire Waterberg is homocygous for the <strong>A2</strong>-type of Beta-Casein.<br />

FLECKVIEHWorld 2010/2011<br />

100<br />

90<br />

80<br />

70<br />

60<br />

50<br />

40<br />

30<br />

20<br />

10<br />

0<br />

AUSTRALIA 23<br />

Allelic frequencies of β-Casein genotypes of different breeds<br />

<strong>Fleckvieh</strong> Holstein Brown Guernsey Milking Jersey<br />

Swiss Shorthorn<br />

<strong>A2</strong> A1 and others<br />

<strong>Fleckvieh</strong> Holstein Brown Guernsey Milking Jersey<br />

Swiss Shorthorn<br />

<strong>A2</strong> 71 % 55 % 66 % 96 % 49 % 50 %<br />

A1 and others 29 % 45 % 34 % 4 % 51 % 50 %<br />

Source: Milk Protein Polymorphisms in Califonia Dairy Cattle, Journal of Dairy Science, Volume 74, Issue 5, May 1991<br />

and Comparison of Influence Markers CSN3 and CSN2 on Milk Performance Traits in Czech Spotted and Holstein<br />

Cattle tested at first, fifth and higehr lactation, Nitra, Slovaca Universitas Agriculturae Nitriae, 2006.


24 AUSTRALIA<br />

Letter to the editor:<br />

Life Changing <strong>Fleckvieh</strong>’s.<br />

By the autumn of 2007, Vikki and I had come to the end of the line with trying to get our 160 Registered Holstein herd to<br />

a workable fertility level. We were at our lowest ebb. Our conception rates had slumped to a low of 10 % and A.I had been<br />

abandoned. We were just running Holstein herd bulls, who could only achieve only slightly better rates of conception,<br />

and broke down under the work load. We had also had abandoned all the herd improvement tools, including herd testing,<br />

as there was very little point of continuing with it as a marketing tool for any surplus cattle, as we had none. We<br />

needed every heifer as a replacement. This was very tedious, as it took 20 doses of semen to yield one heifer. We even<br />

got to the point of buying in <strong>milk</strong>ing cows to keep up our herd numbers. This is the point at which anger and disillusionment<br />

took hold of our souls. When we sought help, the fingers were always pointed at us, and our management. We weren’t<br />

doing this or that right. I can assure you, if your conception rates are as low as 10 %, you leave no stone unturned,<br />

you make sure your management is right!!<br />

Defining Moment<br />

When driving past Chris and Sharon Jordon’s Simmental stud, I got the idea to do something totally out of the square<br />

for me, crossing my registered Holsteins to a Simmental. I knew that the resulting progeny would be very saleable, and<br />

I had always known they had a reputation for high fertility. I had nothing to lose, and my sanity regained.<br />

I by chance took a fancy to a young bull of the <strong>Fleckvieh</strong> strain. He was sired by S.V. Bavarian, and his mother was an<br />

Austrian cow. He was old genetics, the result of a 20 year old stored embryo. As we chatted over the sale and his pedigree,<br />

Chris mentioned that we could <strong>milk</strong> young Bavarian’s daughters and that in fact his mother was herd recorded with<br />

some impressive production figures. Chris also gave me George Cassar’s number. By the time I had young Bavarian<br />

transported home and some semen collected from him, George had some Regio and Hippo semen delivered to my tank.<br />

Another Defining Moment<br />

It was at this time that I did something that people in the industry and people who knew me and my links to the Holstein<br />

breed, found incredible to believe; I tipped out my store of Holstein semen. For me it was an easy thing to do. I am an<br />

all or nothing person. I do my research and then go for it. Three weeks after we started using the <strong>Fleckvieh</strong> semen, our<br />

lifes changed. Around half of the cows I had inseminated held in calf. We took note, but we had been at this point with<br />

the Holsteins, only to see the conception rates deteriorate at 6 weeks and beyond. As we passed 6 weeks and then 3<br />

months, our conceptions were around 45 %. We knew we were back! The pressure release was enormous. We realized<br />

the problem wasn’t with us, it was with the Holstein’s. Three years on and we are waiting for our first F1 <strong>Fleckvieh</strong>’s enter<br />

the <strong>milk</strong>ing herd. We have been able to consistently get our conceptions above 50 %. Just this autumn, I became confident<br />

enough to conduct a synchronized mating program on our maiden F1 <strong>Fleckvieh</strong> heifers. Early conception rates are<br />

outstanding, a figure that we would have only once dreamed about and something George Casser said we would regain<br />

quickly.<br />

Defining Moment No. 3<br />

When our first <strong>Fleckvieh</strong> calves were born, it was then that we realised we had stumbled on to something special. These<br />

were the easiest calves to rear. No more nursing sickly calves. No more did I have the chore of administrating antibiotics,<br />

only to have the calves die in my arms. These F1’s wanted to live, they have a vitality I haven’t seen in calves for 15<br />

years. The next big thrill we got, was when we took our 5 day old bull calves to market. We were used to getting $ 45 for<br />

our Holsteins, with only one or two butchers bidding for them. We were taken aback when a number of calf rearers wanted<br />

to take our calves. The first year, our calves averaged $160 and that average has continued to rise due to the return<br />

buyers keen to reinvest again after seeing first hand how well these calves did. Recently George Cassar sent me some<br />

eartags with „<strong>Fleckvieh</strong>“ printed on them. I make sure that every calf that leaves the property has one of these tags. At<br />

the market I have stood back and watched potential buyers turn the ears and read these tags. Everybody in the market<br />

is now getting comfortable with the way „<strong>Fleckvieh</strong>“ rolls of the auctioneers tongue. At time of writing this article, our F1<br />

<strong>Fleckvieh</strong>’s are 1 month away from calving and they are home, getting accustomed to the dairy/<strong>milk</strong>ing shed and to the<br />

routine of their future <strong>milk</strong>ing lifes. It is a time when we start to get close to them and learn their personalities. We are<br />

also able to observe their conformations and also to compare them with their mothers that are in the herd. We are amazed<br />

that in one generation we are able to totally change the Holstein conformation to that of the <strong>Fleckvieh</strong>. A shape that<br />

will be very suitable to our grass based enterprise. <strong>Fleckvieh</strong> has taken away the tall narrow shoulders and ungainly legs.<br />

They have delivered an animal that will be able to walk distances and graze freely. Their rump set up is something that<br />

we have been searching for for a long time. One area that the naysayers have been trying to knock our confidence on is<br />

udder shape. But as we see them developing on their first calf, we are very confident that the udders will be very adequate<br />

and sound. Vikki has recently remarked to George, how I have regained my confidence to breed good cattle again,<br />

and that I have gotten back my swagger. This has come around because of the tremendous cattle I am seeing before me<br />

on a daily basis, and the potential they are showing me gets me excited.<br />

Go on change your life.<br />

Fire up with <strong>Fleckvieh</strong>!!!!!<br />

Greg Templeton, Australia<br />

FLECKVIEHWorld 2010/2011

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