Presentation

Chhaperone-like
activity ac (%)
Chaperone-like activities of native and mutant monomeric
ββ-CN. CN TTarget t protein t i - iinsulin li
120
100
80
60
40
20
0
0 0,025 0,05 0,075 0,1 0,125
(ß-CN /Insulin) molar ratio
Native β-CN (■), Wild type β-CN (□), C4 β-CN (▲) and C208 β-CN (∆)
The France-Egypt Year Of Science And Technology, 2010
Chemically-induced
aggregation of insulin
performed f di in the th présence é of f
20 mM DTT at 40 °C.
Mutant β-CNs exhibit
considerably smaller
chaperone chaperone-activities activities than that
of native β-CN.