Hormones Control of Lactogenesis and Galactopoiesis
Hormones Control of Lactogenesis and Galactopoiesis
Hormones Control of Lactogenesis and Galactopoiesis
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Oxytocin Release <strong>and</strong> Half-Life<br />
• It is estimated that the bovine pituitary has about<br />
800 micrograms <strong>of</strong> oxytocin. This is about 40X<br />
what is in the blood under resting conditions.<br />
Only about 1/3 <strong>of</strong> pituitary oxytocin is released at<br />
a milking.<br />
• Oxytocin receptors on myoepithelial cells can<br />
respond to very low levels <strong>of</strong> oxytocin.<br />
• Oxytocin has a short half-life in the blood = 0.55<br />
to 3.6 min. This means that the removal <strong>of</strong> milk<br />
by machine or by nursing must be closely timed<br />
with stimulation <strong>of</strong> the teats.