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Hormones Control of Lactogenesis and Galactopoiesis

Hormones Control of Lactogenesis and Galactopoiesis

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Oxytocin Release <strong>and</strong> Half-Life<br />

• It is estimated that the bovine pituitary has about<br />

800 micrograms <strong>of</strong> oxytocin. This is about 40X<br />

what is in the blood under resting conditions.<br />

Only about 1/3 <strong>of</strong> pituitary oxytocin is released at<br />

a milking.<br />

• Oxytocin receptors on myoepithelial cells can<br />

respond to very low levels <strong>of</strong> oxytocin.<br />

• Oxytocin has a short half-life in the blood = 0.55<br />

to 3.6 min. This means that the removal <strong>of</strong> milk<br />

by machine or by nursing must be closely timed<br />

with stimulation <strong>of</strong> the teats.

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