SYMPOSIA

Abstracts of the Invited Speakers
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2. van Praag H. Exercise and the brain: something to chew on. Trends Neurosci 2009;32(5 ):283–90.
3. Little Exercise, Big Effects: Reversing Aging and Infection-Induced Memory Deficits, and Underlying Processes. Barrientos R. M., Frank M.G, Crysdale N.Y, Chapman
T.R, Ahrendsen J.T at all. The Journal of Neuroscience, 2011; 31(32):11578 –86.
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6. van Praag H. Neurogenesis and exercise: past and future directions. Neuromolecular Med. 2008;10(2):128-40.
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Bulletin of Clinical Psychopharmacology 2011;21(Suppl. 2):S91-2
[PS-20]
Symposium Title: Controversial topics in eating disorders
Comorbidities in eating disorders
Atila Erol
Sakarya University, School of Medicine, Department of Psychiatry, Sakarya, Turkey
E-mail: erolatila@gmail.com
Patients with eating disorders exhibit high rates of psychiatric comorbidity and the number of comorbid psychiatric disorders is high.
The treatment of co-occurring psychiatric problems in eating disordered patients is essential for good clinical management and the
outcome of treatments. Higher rates of comorbidity often mean greater severity, treatment resistance and poor outcomes in eating
disorders. The most prevalent Axis I disorders seem to be mood and anxiety disorders, alcohol and substance abuse, and bipolar disorder.
Axis II disorders are also common. At least 80% of anorexia nervosa (AN) or bulimia nervosa (BN) patients have at least one additional
psychiatric disorder over their lifetime. Mood disorders are very common among patients with AN. Major depressive disorder occurs in
50-70% of AN patients. Bulimic patients have 52-75% affective disorder, with 63% having major depression. Lifetime prevalence rates of
major depression in BN are 50-65%.
Among study samples with restricting and binging /purging anorexia nervosa, prevalence rates of any anxiety disorder are found to be
between 24% and 71%, respectively. Among patients with BN prevalence rates for any anxiety disorder, social phobia, generalised anxiety
disoder (GAD) or panic disorder are reported to be 36%, 17%, 12% and 10% respectively. The approximate rates of any anxiety disorder in
BN are reported to be between 57 and 75 %.
Thirty-five percent of restricting AN patients have obsessive compulsive disorder (OCD) and binging/purging AN patients have 44% OCD.
BN patients have comorbid OCD 40% of the time. Lifetime prevalence rates of substance abuse in AN ranged from 12% to 18% and in
BN the rates ranged from 30% to 70%. The results of clinical studies indicate that patients with BPD have higher rates of eating disorders
compared with the general population. Rates of lifetime BPD in eating disorders patients are variable but higher than rates of BPD in the
general population. Among eating disorder patients post-traumatic stress disorder rates were found between 8% to 11%.
Key words: Eating disorders, anorexia, bulimia, comorbidity
Bulletin of Clinical Psychopharmacology 2011;21(Suppl. 2):S92
S92 Bulletin of Clinical Psychopharmacology, Vol: 21, Supplement: 2, 2011 - www.psikofarmakoloji.org