SYMPOSIA
SYMPOSIA
SYMPOSIA
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Abstracts of the Invited Speakers<br />
References:<br />
1. Lista I, Sorrentino G. Biological mechanisms of physical activity in preventing cognitive decline. Cell Mol Neurobiol. 2010;30(4):493-503.<br />
2. van Praag H. Exercise and the brain: something to chew on. Trends Neurosci 2009;32(5 ):283–90.<br />
3. Little Exercise, Big Effects: Reversing Aging and Infection-Induced Memory Deficits, and Underlying Processes. Barrientos R. M., Frank M.G, Crysdale N.Y, Chapman<br />
T.R, Ahrendsen J.T at all. The Journal of Neuroscience, 2011; 31(32):11578 –86.<br />
4. Christofoletti G, Oliani M.M, Bucken L.T, Gobbi S, Beinotti F, Stella F. Physical activity attenuates neuropsychiatric disturbances and caregiver burden in patients<br />
with dementia. Clinics (Sao Paulo). 2011; 66(4): 613–8.<br />
5. Ma Q. Beneficial effects of moderate voluntary physical exercise and its biological mechanisms on brain health. Neurosci Bull. 2008;24(4):265-70.<br />
6. van Praag H. Neurogenesis and exercise: past and future directions. Neuromolecular Med. 2008;10(2):128-40.<br />
7. Ang. ET, Tai YK, Lo SQ, Seet R, Soong TW.Neurodegenerative Diseases: Exercising Toward Neurogenesis and Neuroregeneration. Front Aging Neurosci. 2010; 2: 25.<br />
8. Tomporowski P. D., Lambourne K., Okumura M. S. Physical activity interventions and children’s mental function: an introduction and overview. Prev Med. 2011;<br />
52(Suppl 1): S3–S9.<br />
9. Fadillioglu E., Kaya B., Uz E., Emre M.H., Ünal S. Effects of Moderate Exercise on Mild Depressive Mood, Antioxidants and Lipid Peroxidation. Bull Clin<br />
Psychopharmacol 2000; 10(4):194-200.<br />
Bulletin of Clinical Psychopharmacology 2011;21(Suppl. 2):S91-2<br />
[PS-20]<br />
Symposium Title: Controversial topics in eating disorders<br />
Comorbidities in eating disorders<br />
Atila Erol<br />
Sakarya University, School of Medicine, Department of Psychiatry, Sakarya, Turkey<br />
E-mail: erolatila@gmail.com<br />
Patients with eating disorders exhibit high rates of psychiatric comorbidity and the number of comorbid psychiatric disorders is high.<br />
The treatment of co-occurring psychiatric problems in eating disordered patients is essential for good clinical management and the<br />
outcome of treatments. Higher rates of comorbidity often mean greater severity, treatment resistance and poor outcomes in eating<br />
disorders. The most prevalent Axis I disorders seem to be mood and anxiety disorders, alcohol and substance abuse, and bipolar disorder.<br />
Axis II disorders are also common. At least 80% of anorexia nervosa (AN) or bulimia nervosa (BN) patients have at least one additional<br />
psychiatric disorder over their lifetime. Mood disorders are very common among patients with AN. Major depressive disorder occurs in<br />
50-70% of AN patients. Bulimic patients have 52-75% affective disorder, with 63% having major depression. Lifetime prevalence rates of<br />
major depression in BN are 50-65%.<br />
Among study samples with restricting and binging /purging anorexia nervosa, prevalence rates of any anxiety disorder are found to be<br />
between 24% and 71%, respectively. Among patients with BN prevalence rates for any anxiety disorder, social phobia, generalised anxiety<br />
disoder (GAD) or panic disorder are reported to be 36%, 17%, 12% and 10% respectively. The approximate rates of any anxiety disorder in<br />
BN are reported to be between 57 and 75 %.<br />
Thirty-five percent of restricting AN patients have obsessive compulsive disorder (OCD) and binging/purging AN patients have 44% OCD.<br />
BN patients have comorbid OCD 40% of the time. Lifetime prevalence rates of substance abuse in AN ranged from 12% to 18% and in<br />
BN the rates ranged from 30% to 70%. The results of clinical studies indicate that patients with BPD have higher rates of eating disorders<br />
compared with the general population. Rates of lifetime BPD in eating disorders patients are variable but higher than rates of BPD in the<br />
general population. Among eating disorder patients post-traumatic stress disorder rates were found between 8% to 11%.<br />
Key words: Eating disorders, anorexia, bulimia, comorbidity<br />
Bulletin of Clinical Psychopharmacology 2011;21(Suppl. 2):S92<br />
S92 Bulletin of Clinical Psychopharmacology, Vol: 21, Supplement: 2, 2011 - www.psikofarmakoloji.org