SYMPOSIA
SYMPOSIA
SYMPOSIA
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Abstracts of the Invited Speakers<br />
References:<br />
1. McEwen BS Steroid hormones are multifunctional messengers to the brain. Horm Res. 1992; 37(Suppl 3):1-10.<br />
2. Genazzani A.R. et al. Endocrinology of Menopausal Transition and Its Brain Implications CNS Spectr. 2005 Jun;10(6):449-57.<br />
3. Janice R, Stevens MD Schizophrenia: reproductive hormones and the brain. Am J Psychiatry 2002; 159:713-719.<br />
4. Seeman MV. The role of estrogen in schizophrenia. J Psychiatry Neurosci 1996; 21:123-125.<br />
5. Zarrouf FA, Artz S, Griffith J, Sirbu C, Kommor M. Testosterone and depression: systematic review and meta-analysis. J Psychiatr Pract 2009;15:289-305.<br />
6. Hall, R. C. W., Hall, R. C. W. & Chapman, M. J. Psychiatric complications of anabolic steroid use. Psychosomatics, 2005; 46- 285.<br />
Bulletin of Clinical Psychopharmacology 2011;21(Suppl. 2):S77-8<br />
Insulin and psychiatric disorders<br />
Mesut Cetin<br />
Department of Psychiatry, GATA Haydarpasa Training Hospital, Uskudar, Istanbul, Turkey<br />
E-mail: mesutcetin@yahoo.com<br />
Insulin is a hormone central to regulating carbohydrate and fat metabolism in the body. Insulin also influences other body functions, such<br />
as enhancing acute thermoregulatory and glucoregulatory responses to food intake. It is also a neuropeptide transmitter and enhances<br />
learning and memory.<br />
Hypoglycemia is a lack of sufficient glucose and a scarcity of the sources of glucose, which can dramatically manifest itself with impaired<br />
functioning of the central nervous system and can cause dizziness, speech problems, and even loss of consciousness. While producing<br />
those symptoms, hypoglycemia also provokes a rapid increase in epinephrine secretion, which leads to tremulousness, lightheadedness,<br />
perspiration, anxiety, hunger, nausea, and tachycardia. These symptoms present like a panic attack, suggesting that if hypoglycemia does<br />
provoke anxiety attacks it may be through its action as a nonspecific stressor, perhaps by interacting with an underlying CNS disorder<br />
that predisposes to panic. The fear of hypoglycemia-induced bodily symptoms of arousal has been implicated in the pathogenesis of<br />
both spontaneously occurring and experimentally provoked panic attacks. The fear of bodily symptoms may be a characteristic of panic<br />
disorder and is hypothesized to predict state anxiety and panic frequency during experimentally induced peripheral arousal.<br />
Insulin resistance and metabolic syndrome (MS) have become worldwide problems. MS is a cluster of risk factors associated with<br />
increased risk of cardiovascular diseases and type 2 diabetes. Based on research data from 2004, 40% of adults in Turkey meet the criteria<br />
for diagnosis of metabolic syndrome. The use of certain medications, such as atypical antipsychotics, may increase insulin resistance and<br />
the risk of the metabolic syndrome.<br />
Key words: Insulin, panic disorder, insulin resistance, hypoglycemia, depression<br />
Bulletin of Clinical Psychopharmacology 2011;21(Suppl. 2):S78<br />
[PS-14]<br />
Symposium Title: Clinical course of psychiatric disorders associated with trauma and treatment issues<br />
Trauma and mood disorders<br />
Medine Yazıcı Güleç<br />
Erenkoy Mental Research and Training Hospital, Istanbul, Turkey<br />
E-mail: drmedineyazici@yahoo.com, medineyazici@hotmail.com<br />
There is increasing evidence for the role of adverse childhood experiences in the occurence of mood disorders (MD). A great number of<br />
studies have shown that there is a correlation between MD and parental indifference, neglect and sexual and physical abuse. Angst et<br />
al., in a 20-year longitudinal study, suggested that childhood family issues have a robust correlation with the chronicity of bipolar and<br />
unipolar MD, and adverse childhood experiences give rise to low self-esteem and anxious personality. The presence of childhood trauma<br />
(CT) has found to be associated with increases in rates of substance abuse, early age of onset, rapid cycling, and suicide. There is severe<br />
CT in half (49%) of bipolar MD patients.<br />
S78 Bulletin of Clinical Psychopharmacology, Vol: 21, Supplement: 2, 2011 - www.psikofarmakoloji.org