SYMPOSIA
SYMPOSIA
SYMPOSIA
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Abstracts of the Invited Speakers<br />
Studies show that effective treatment significantly improves quality of life (3). Severity of childhood ADHD and treatment significantly<br />
predict the persistence of ADHD into adulthood (5). As previously shown by some research for children and adolescents, stimulant<br />
medications alone did not eliminate the academic achievement deficit of ADHD undergraduates. ADHD patients who were treated with<br />
stimulants were significantly less likely to subsequently develop depressive and anxiety disorders and disruptive behavior and less likely to<br />
repeat a grade compared with participants with ADHD who were not treated. Adolescents with ADHD were also significantly more likely<br />
to be absent during the academic year, and they were over eight times more likely than adolescents without ADHD to drop out of high<br />
school. These findings demonstrate that children with ADHD continue to experience severe academic impairment into high school (10).<br />
Key words: Attention deficit hyperactivity, academic performance, occupation<br />
References:<br />
1. Barkley RA. Major life activity and health outcomes associated with attention-deficit / hyperactivity disorder. J. Clin Psychiatry 2002;63 12:10-15.<br />
2. Weiss G, Hechtman L. Hyperactive Children Grown Up: ADHD in Children, Adolescents, and Adults. New York, NY: Guilford Press; 1993<br />
3. Cheng K, Myers KM, Stubble DE. Attention deficit hyperactivity disorder Child and Adolescent Psychiatry The Essentials Lippincott Williams &Wilkins<br />
4. Biederman J, Mick E, Faraone SV. Age dependent decline of symptoms of attention deficit hyperactivity disorder: Impact of remission definition and symptoms<br />
type. Am J Psychiatry 2000 157:816-818<br />
5. Sadock BJ, Sadock VA. Textbook of Child and Adolescent Psychiatry. 2009 Lippincott Williams &Wilkins<br />
6. Culpaper L, Mattingly G. Challenges in Identifying and Managing Attention-Deficit/Hyperactivity Disorder in Adults in the Primary Care Setting: A Review of the<br />
Literature Prim Care Companion J Clin Psychiatry 2010 v. 12(6);<br />
7. McCann BS, Roy-Byrne P Attention-deficit/hyperactivity disorder and learning disabilities in adults. Semin Clin Neuropsychiatry. 2000 Jul;5(3):191-7.<br />
8. Spetie L, Arnold EL. Attention deficit hyperactivity disorder in Lewis Child and Adolescent Psychiatry A Comprehensive Textbook 2007 Lippincott Williams &Wilkins<br />
9. Lam AK, Ho TP Early adolescent outcome of attention-deficit hyperactivity disorder in a Chinese population: 5-year follow-up study. J Fam Pract. 2011 Jun;60(6):364-7.<br />
10. Kent KM, Pelham WE Jr, Molina BS, Sibley MH, Waschbusch DA, Yu J, Gnagy EM, Biswas A, Babinski DE, Karch KM.The academic experience of male high school<br />
students with ADHD.Pediatrics. 2009 Jul;124(1):71-8.<br />
Bulletin of Clinical Psychopharmacology 2011;21(Suppl. 2):S57-8<br />
[PS-05]<br />
Symposium Title: Brain mapping, TMS, NVS, biofeedback and deep brain stimulation in treatment of psychiatric disorders<br />
Concomitant use of qEEG and rTMS in treatment of depressive disorder, new approaches<br />
Nevzat Tarhan, Gökben Hızlı, Serap Aydın<br />
Üsküdar University, Neuropsychiatry Istanbul Hospital, Istanbul, Turkey<br />
E-mail: ntarhan@uskudar.edu.tr, ntarhan@gmail.com<br />
Repetitive transcranial magnetic stimulation (rTMS) therapy has been approved for treatment of depression by the FDA in 2008, and was<br />
included in APA Guidelines as published in October, 2010 issue of American Journal of Psychiatry. Although its efficacy is not as high as<br />
the efficacy of ECT, rTMS is safer in the treatment of depression in older patients. Especially the absence of common treatment side effects<br />
of ECT, such as confusion and memory problems, makes rTMS treatment more valuable in patients with high side effect risk.<br />
This study was performed by the quantitative EEG (qEEG) monitoring before and after rTMS treatment. The aim was to examine the<br />
predictive value of qEEG as a biological indicator of response to rTMS treatment.<br />
In Neuropsychiatry Istanbul Hospital, between dates of 2006-2010, rTMS had been applied to 1283 patients with a diagnosis of treatmentresistant<br />
depressive disorder. The patients discontinued the psychotropic medications 12 hours before the qEEG monitoring. qEEG records were<br />
taken just before the first and the last rTMS sessions. HAM-D 17 was performed before and after 15-20 (mean was 18) sessions of rTMS treatment.<br />
The patients with a medical history of epilepsy were excluded. The cases with no history of seizures, but with suspicious epileptical<br />
abnormality in pre-treatment EEG were included with special medical caution. rTMS treatment was performed at left DLPFC, as 25 hz. and<br />
1000 pulse, one session on each day, a total of 15-20 sessions, with Magstim Rapid.<br />
From 1283 cases, one patient had epileptic seizure as an adverse effect. Due to contraction of facial muscles, one patient had a broken<br />
tooth. In 3 patients suffering from tinnitus occurred, but later tinnitus decreased significantly.<br />
The statistical analyses of the cases are ongoing. The initial results with remission and response rates will be presented. qEEG power<br />
spectrum changes and changes in the activation compared to normative data base in LORETA will be evaluated.<br />
Key words: Repetitive transcranial magnetic stimulation (rTMS) therapy, quantitative EEG, depression treatment<br />
Bulletin of Clinical Psychopharmacology 2011;21(Suppl. 2):S58<br />
S58 Bulletin of Clinical Psychopharmacology, Vol: 21, Supplement: 2, 2011 - www.psikofarmakoloji.org