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Bulletin of Clinical Psychopharmacology, Vol: 21, Supplement: 2, 2011 - www.psikofarmakoloji.org<br />

Poster Presentations<br />

that the cerebellum has a role in the general dyscoordination of sensorimotor and mental processes which are seen in schizophrenic patients.<br />

The following observations demonstrating the involvement of the cerebellum are determined in studies of schizophrenic patients: high<br />

prevalence of neurological soft signs, dyscoordination, abnormal posture, balance problems, impaired eye blink conditioning and impaired<br />

adaptation of the vestibular-ocular reflex. Abnormal cerebellar activations have been showed in functional imaging studies. In the context of<br />

this case, the relationship of schizophrenia with cerebellar anomalies was reviewed.<br />

Key words: Schizophrenia, mega cisterna magna, cerebellum, brain imaging methods<br />

Bulletin of Clinical Psychopharmacology 2011;21(Suppl. 2):S194-5<br />

[PP-118] Ref. No: 263<br />

Congenital hypogonadism and comorbid anorexia nervosa in a male patient:<br />

A case report<br />

Mustafa Özten, Atila Erol<br />

Department of Psychiatry, Sakarya University, Sakarya, Turkey<br />

E-mail: drozten@yahoo.com<br />

Male hypogonadism results from a failure of the testes to produce adequate androgen. Patients have low circulating testesterone in<br />

combination with clinical symptoms such as osteopenia, increased adiposity, decreased muscle mass, decline in energy and stamina,<br />

decreased cognitive function, decreased libido and erectile dysfunction. The cause may be primary (genetic anomaly) or secondary (defect in<br />

hypothalamus or pituitary), but often presents with the same symptomatology. Hypogonadal patients who are both symptomatic and who<br />

have clinically significant alterations in laboratory values are candidates for treatment. Testosterone replacement therapy is widely applied.<br />

The prevalence of eating disorders in men as compared to women is less than ten times and also shows differences in the course of the<br />

disease and the causes of its appearance. Social, genetic, psychological factors, personality traits and a history of trauma are considered to<br />

play a role in the development of anorexia nervosa (AN). In addition, steroid hormones affect the development of eating disorders and eating<br />

behavior. Homosexuality, asexuality and sexual role disorders are known to be more common in male patients with AN. AN is associated<br />

with notable medical complications and affects many systems like a general medical disease. One of the systems that is affected by AN is<br />

the genitourinary system; hypogonadism is one of the known complications of AN. Endocrine abnormalities such as hypogonadotropic<br />

hypogonadism mediate some of the clinical manifestations. Most of the endocrine changes that occur in AN are physiological adaptations<br />

to starvation and are usually reversible with weight gain. Prolonged AN or cachexia can cause hypogonadism. In this article we report a<br />

man, who had suffered from hypogonadism since infancy with no treatment and developed AN at age 18. Congenital hypogonadism with<br />

comorbid AN is a rare illness. As a result of the interaction of hypogonadism with anorexia nervosa the patient developed a sexual identity<br />

crisis, which is important in its clinical and theoretical aspects, since he suffered from delayed puberty, no secondary sexual characteristics,<br />

and no ejaculation or erection although he was 22 years old. Up to now only one case from Japan is reported in the literature with congenital<br />

hypogonadism and anorexia nervosa. Hypogonadism with comorbid anorexia nervosa has not been listed as a case in the Turkish indices yet.<br />

Key words: Anorexia nervosa, congenital hypogonadism, male patient<br />

Bulletin of Clinical Psychopharmacology 2011;21(Suppl. 2):S195<br />

[PP-119] Ref. No: 275<br />

Review of diagnosis and treatment of pregnant psychiatric patients in a state hospital<br />

Kader Semra Karataş, Jülide Güler, Aytül Hariri<br />

Erenkoy Mental and Nervous Diseases Training and Research Hospital, Department of Psychiatry, İstanbul, Turkey<br />

E-mail: drsemraocak@yahoo.com<br />

Background: Because of the physiological changes during pregnancy there are changes of pharmacokinetic and pharmacodynamic<br />

characteristics, and there are differences in the treatment of psychiatric disorders in this period.<br />

Objective: The aim of this study was to evaluate the sociodemographical features, diagnoses, and treatments of 20 pregnant psychiatric<br />

inpatients that were hospitalized between August 2010 and August 2011.<br />

Method: The sociodemographical features, diagnoses, and treatments of the patients were evaluated retrospectively.<br />

Results: The percentages of diagnoses of the patients were as follows: schizophrenia 27.3%, bipolar affective disorder manic episode<br />

S195

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