SYMPOSIA
SYMPOSIA
SYMPOSIA
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Poster Presentations<br />
References:<br />
1. Jin H., Meyer J.M., Mudaliar S., Jeste D.V., 2008. Impact of atypical antipsychotic therapy on leptin, ghrelin, and adiponectin. Schizophrenia Research 100 (2008)<br />
70–85.<br />
2. Yazıcı K. Yazıcı A., 2008. Weight Increase Induced by Antipsychotic drugs:What is the role of genes? Bulletin of Clinical Psychopharmacology 2008;18:59-70.<br />
3. Chagnon YC. Susceptibility genes for the side effect of antipsychotics on body weight and obesity.Curr Drug Targets 2006; 12: 1681-1695<br />
4. Evans WE, Johnson JA. Pharmacogenomics: the inherited basis for interindividual differences in drug response. Annu Rev Genomics Hum Genet 2001; 2: 9-39<br />
Bulletin of Clinical Psychopharmacology 2011;21(Suppl. 2):S171-2<br />
[PP-084] Ref. No: 183<br />
Do cultural factors effect clinical manifestations of OCD? Clinical features of<br />
a Turkish sample<br />
Ramazan Konkan 1 , Ömer Şenormancı 1 , Oya Güçlü 1 , Erkan Aydın 1 , Mehmet Z. Sungur 2<br />
1 Bakırköy Research and Training Hospital for Psychiatry, Neurology and Neurosurgery, İstanbul, Turkey<br />
2 Marmara University School of Medicine, İstanbul, Turkey<br />
E-mail: ramazankonkan@gmail.com<br />
Objective: In the present study we evaluated the clinical characteristics of OCD patients monitored in an outpatient program and<br />
compared them with other cultures.<br />
Method: The study included 116 OCD patients who presented to the clinics at the Bakirköy Research and Training Hospital for Psychiatry,<br />
Neurology and Neurosurgery, met the inclusion criteria, volunteered to participate in the study after being diagnosed and were referred<br />
by two psychiatrists. The diagnosis was confirmed using the Structured Clinical Interview Form for the DSM-IV Axis I Disorders (SCID-I). An<br />
inquiry form was developed for obsessive compulsive symptoms based on the obsessions and compulsions included in the Yale-Brown<br />
Obsession Compulsion Scale (Y-BOCS) according to their incidence and a sociodemographic form from the SCID-I clinical interview guide.<br />
Results: Our sample consisted of 30 male (25.9%) and 86 female (74.1%) patients. The mean age was 34.96±10.23 years. The most<br />
common obsessions were impurity-contamination (49.1%), followed by doubt (20.7%) and religious (11.2%) obsessions. Secondary<br />
obsessions included doubt (53.4%), impurity-contamination (14.7%) and sexual obsessions (9.5%), respectively. In tertiary obsessions,<br />
21 patients reported presence of symmetry-exactness (18.1%), 13 patients reported doubt (11.2%), 10 patients reported sexual (8.6%)<br />
obsessions, and 43 patients (37.1%) had no tertiary obsessions (Table 1). Ninety-six percent of patients had accompanying compulsions.<br />
The most common compulsions were cleaning and washing (53.4%), checking (26.7%) and repetitive ritual behavior (7.8%).DISCUSSION:<br />
The most common obsession in the present study was impurity/contamination with a rate of 49.1% in line with the literature, followed by<br />
doubt obsessions of 20.7%. The most common compulsion reported in literature is washing accompanied by obsession of contamination,<br />
and it is followed by checking. Similarly, in our study, the primary compulsion was cleaning and washing with a rate of 53.4%, followed by<br />
checking (26.7%) and repetitive ritual behaviors (7.8%). Although the first two obsessions and compulsions are in line with the literature,<br />
the tertiary obsessions reported as aggressive or sexual obsessions in the literature were replaced by religious obsessions (11.2%) in our<br />
sample. An intercultural study showed that religious obsessions were the most common obsessions with 60% in the Egyptian sample,<br />
and 50% in the Saudi sample. However, the rate of religious obsessions was 6% in the U.S., 5% in the United Kingdom, and 11% in India.<br />
Studies on Jewish populations showed similar results with the Muslim populations, with a religious obsession rate of 50%. We believe that<br />
the rate of religious obsession is associated with our country’s position, being at the junction of Western and Eastern cultures. Relatively<br />
lower rate of sexual obsessions compared to the literature may result from the fact that obsessions related with sexuality may be more<br />
difficult to report than other obsessions in our population.<br />
Key words: Clinical manifestation, cultural differences, OCD<br />
Bulletin of Clinical Psychopharmacology 2011;21(Suppl. 2):S172<br />
S172 Bulletin of Clinical Psychopharmacology, Vol: 21, Supplement: 2, 2011 - www.psikofarmakoloji.org