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Poster Presentations<br />

4. Şükrü Kartalcı, Işıl Göğceğöz Gül, Rıfat Karlıdağ, Birgül Elbozan Cumurcu Recurrent priapism during quetiapine treatment case report; Bulletin of Clinical<br />

Psychopharmacology, Vol: 20, N.: 4, 2010 327-328<br />

Bulletin of Clinical Psychopharmacology 2011;21(Suppl. 2):S167-8<br />

[PP-078] Ref. No: 113<br />

Prescribing patterns and inappropriate use of medications in patients referred to<br />

doctors in Ardabil City of Iran<br />

Firouz Amani, Amin Shaker<br />

Iran- Ardabil University of Medical Sciences, Iran<br />

E-mail: biostat.f@gmail.com<br />

Objective: To determine the drug use patterns and descriptive analysis of prescriptions among patients who visited doctors in Ardabil City.<br />

Methods: A retrospective study was carried out on 2000 randomly selected prescriptions from all registered prescriptions in Ardabil City<br />

using data from two insurance organizations. Data were obtained on demographics, prescribing indicators and potentially inappropriate<br />

medications. The collected data were analyzed by descriptive statistical methods using SPSS software.<br />

Results: From all prescriptions, 822 (41 %) were for men and 1178 (59%) were for women. The mean age of the subjects was 31.6 ± 21.3<br />

years ranging from 1 to 91. On thousand three hundred and six (65.3%) of all prescriptions were from general practitioners and others from<br />

specialists. The mean number of drugs per prescription was 3.58±1.3 ranging from 1 to 9. Dexamethasone, with 219 (24.7 %) prescriptions,<br />

was the most commonly prescribed medication. The total number of medications prescribed in all the prescriptions was 7158 while the<br />

mean number of medications per encounter was 3.6. Antibiotics, with 52.8% of the prescriptions, were the most prescribed drug group.<br />

Conclusion: The results showed that the mean of prescription drugs per encounter and the rate of prescription injection drugs were more<br />

than the global standards. Also, the pattern of prescription drugs was inappropriate. It is necessary to reduce irrational prescription of<br />

drugs to patients by monitoring and control indicators of medical doctors who prescribe higher numbers of prescriptions.<br />

Key words: Pattern, drug utilization, inappropriate medications<br />

Bulletin of Clinical Psychopharmacology 2011;21(Suppl. 2):S168<br />

[PP-079] Ref. No: 305<br />

Bipolar affective disorder and normal pressure hydrocephaly: A case report<br />

Kader Semra Karataş 1 , Jülide Güler 1 , Özgür Bilgin Topçuoğlu 2 , Ebru Damla Bostancı 1 , Beliz Soyer 1<br />

1Erenkoy Mental and Nervous Diseases Training and Research Hospital, Department of Psychiatry, İstanbul, Turkey<br />

2Erenkoy Mental and Nervous Diseases Training and Research Hospital, Department of Neurology, İstanbul, Turkey<br />

E-mail: drsemraocak@yahoo.com<br />

Background: The subject of this study was how affective disorders are related to structural changes in the brain. The use of lithium in<br />

affective disorders can cause pseudotumor cerebri, which has been reported in the literature, although there is no information about the<br />

occurrence of normal pressure hydrocephalus. We detected normal pressure hydrocephalus in a patient diagnosed with bipolar affective<br />

disorder 10 years ago and treated with lithium.<br />

Case: A 55 year-old woman, housewife, not working, lives in Istanbul with her husband and children. She was diagnosed with bipolar<br />

affective disorder 10 years ago and treated with lithium. She had hand tremors, weakness and dizziness and was admitted to hospital.<br />

The patient was dehydrated, walking with small steps, showed balance difficulty and urinary incontinence. The patient was admitted<br />

to the psychiatric unit. A neurology consultation and cranial MRI were requested. The patient was thought to have normal pressure<br />

hydrocephalus. Lumbar puncture was performed twice. The patient was diagnosed with arrested hydrocephalus; CSF flow could not be<br />

identified. A CSF dynamic MRI was requested and the patient was transferred to neurosurgery.<br />

Discussion: There are publications about the relationship between structural brain abnormalities and affective disorders. Hydrocephalus,<br />

by definition, is the accumulation of CSF in the ventricular system due to an imbalance between production and absorption of CSF.<br />

Presenting symptoms include memory impairment, urinary incontinence symptoms, and ventriculomegaly (2,3). The etiology of<br />

normal pressure hydrocephalus can include head trauma, metabolic problems, endocrinopathies, infectious and immunological<br />

conditions; danazol, tamoxifen, oxytocin, tetracycline, indomethacin, lithium, drugs such as retinol are mentioned (2.4). Normal pressure<br />

S168 Bulletin of Clinical Psychopharmacology, Vol: 21, Supplement: 2, 2011 - www.psikofarmakoloji.org

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