Experimental infection and protection against ... - TI Pharma
Experimental infection and protection against ... - TI Pharma Experimental infection and protection against ... - TI Pharma
Protection against a Malaria Challenge by Sporozoite Inoculation 187 infected mosquitoes. We acknowledge the safety monitors on this study, B. Schouwenberg & P. Smits and independent physician A. Brouwer. Funding Supported by the Dioraphte Foundation, by a fellowship from the European Union FP6 Network of Excellence (to Dr. McCall), and by grants from the NutsOhra Foundation (to Dr. van der Ven) and Agence Nationale de la Recherche in France (to Dr. Snounou).
188 Chapter 9 References 1. Greenwood BM, Fidock DA, Kyle DE et al. Malaria: progress, perils, and prospects for eradication. J Clin Invest 2008; 118:1266-76. 2. Clyde DF, Most H, McCarthy VC, Vanderberg JP. Immunization of man against sporozite-induced falciparum malaria. Am J Med Sci 1973; 266:169-77. 3. Nussenzweig RS, Vanderberg J, Most H, Orton C. Protective immunity produced by the injection of x-irradiated sporozoites of plasmodium berghei. Nature 1967; 216:160-2. 4. Mellouk S, Lunel F, Sedegah M, Beaudoin RL, Druilhe P. Protection against malaria induced by irradiated sporozoites. Lancet 1990; 335:721. 5. Hoffman SL, Goh LM, Luke TC et al. Protection of humans against malaria by immunization with radiation-attenuated Plasmodium falciparum sporozoites. J Infect Dis 2002; 185:1155-64. 6. Alonso PL, Sacarlal J, Aponte JJ et al. Duration of protection with RTS,S/AS02A malaria vaccine in prevention of Plasmodium falciparum disease in Mozambican children: single-blind extended follow-up of a randomised controlled trial. Lancet 2005; 366:2012-8. 7. Abdulla S, Oberholzer R, Juma O et al. Safety and immunogenicity of RTS,S/AS02D malaria vaccine in infants. N Engl J Med 2008; 359:2533-44. 8. Bejon P, Lusingu J, Olotu A et al. Efficacy of RTS,S/AS01E vaccine against malaria in children 5 to 17 months of age. N Engl J Med 2008; 359:2521-32. 9. Aponte JJ, Aide P, Renom M et al. Safety of the RTS,S/AS02D candidate malaria vaccine in infants living in a highly endemic area of Mozambique: a double blind randomised controlled phase I/IIb trial. Lancet 2007; 370:1543-51. 10. Beaudoin RL, Strome CP, Mitchell F, Tubergen TA. Plasmodium berghei: immunization of mice against the ANKA strain using the unaltered sporozoite as an antigen. Exp Parasitol 1977; 42:1-5. 11. Yayon A, Vande Waa JA, Yayon M, Geary TG, Jensen JB. Stage-dependent effects of chloroquine on Plasmodium falciparum in vitro. J Protozool 1983; 30:642-7. 12. Belnoue E, Costa FT, Frankenberg T et al. Protective T cell immunity against malaria liver stage after vaccination with live sporozoites under chloroquine treatment. J Immunol 2004; 172:2487-95. 13. Ponnudurai T, Lensen AH, van Gemert GJ, Bensink MP, Bolmer M, Meuwissen JH. Infectivity of cultured Plasmodium falciparum gametocytes to mosquitoes. Parasitology 1989; 98 Pt 2:165-73. 14. Rombo L, Bergqvist Y, Hellgren U. Chloroquine and desethylchloroquine concentrations during regular long-term malaria prophylaxis. Bull World Health Organ 1987; 65:879-83.
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188 Chapter 9<br />
References<br />
1. Greenwood BM, Fidock DA, Kyle DE et al. Malaria: progress, perils, <strong>and</strong><br />
prospects for eradication. J Clin Invest 2008; 118:1266-76.<br />
2. Clyde DF, Most H, McCarthy VC, V<strong>and</strong>erberg JP. Immunization of man <strong>against</strong><br />
sporozite-induced falciparum malaria. Am J Med Sci 1973; 266:169-77.<br />
3. Nussenzweig RS, V<strong>and</strong>erberg J, Most H, Orton C. Protective immunity produced<br />
by the injection of x-irradiated sporozoites of plasmodium berghei. Nature<br />
1967; 216:160-2.<br />
4. Mellouk S, Lunel F, Sedegah M, Beaudoin RL, Druilhe P. Protection <strong>against</strong><br />
malaria induced by irradiated sporozoites. Lancet 1990; 335:721.<br />
5. Hoffman SL, Goh LM, Luke TC et al. Protection of humans <strong>against</strong> malaria by<br />
immunization with radiation-attenuated Plasmodium falciparum sporozoites. J<br />
Infect Dis 2002; 185:1155-64.<br />
6. Alonso PL, Sacarlal J, Aponte JJ et al. Duration of <strong>protection</strong> with RTS,S/AS02A<br />
malaria vaccine in prevention of Plasmodium falciparum disease in Mozambican<br />
children: single-blind extended follow-up of a r<strong>and</strong>omised controlled trial.<br />
Lancet 2005; 366:2012-8.<br />
7. Abdulla S, Oberholzer R, Juma O et al. Safety <strong>and</strong> immunogenicity of<br />
RTS,S/AS02D malaria vaccine in infants. N Engl J Med 2008; 359:2533-44.<br />
8. Bejon P, Lusingu J, Olotu A et al. Efficacy of RTS,S/AS01E vaccine <strong>against</strong> malaria<br />
in children 5 to 17 months of age. N Engl J Med 2008; 359:2521-32.<br />
9. Aponte JJ, Aide P, Renom M et al. Safety of the RTS,S/AS02D c<strong>and</strong>idate malaria<br />
vaccine in infants living in a highly endemic area of Mozambique: a double blind<br />
r<strong>and</strong>omised controlled phase I/IIb trial. Lancet 2007; 370:1543-51.<br />
10. Beaudoin RL, Strome CP, Mitchell F, Tubergen TA. Plasmodium berghei:<br />
immunization of mice <strong>against</strong> the ANKA strain using the unaltered sporozoite as<br />
an antigen. Exp Parasitol 1977; 42:1-5.<br />
11. Yayon A, V<strong>and</strong>e Waa JA, Yayon M, Geary TG, Jensen JB. Stage-dependent effects<br />
of chloroquine on Plasmodium falciparum in vitro. J Protozool 1983; 30:642-7.<br />
12. Belnoue E, Costa FT, Frankenberg T et al. Protective T cell immunity <strong>against</strong><br />
malaria liver stage after vaccination with live sporozoites under chloroquine<br />
treatment. J Immunol 2004; 172:2487-95.<br />
13. Ponnudurai T, Lensen AH, van Gemert GJ, Bensink MP, Bolmer M, Meuwissen<br />
JH. Infectivity of cultured Plasmodium falciparum gametocytes to mosquitoes.<br />
Parasitology 1989; 98 Pt 2:165-73.<br />
14. Rombo L, Bergqvist Y, Hellgren U. Chloroquine <strong>and</strong> desethylchloroquine<br />
concentrations during regular long-term malaria prophylaxis. Bull World Health<br />
Organ 1987; 65:879-83.
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