towards improved death receptor targeted therapy for ... - TI Pharma
towards improved death receptor targeted therapy for ... - TI Pharma
towards improved death receptor targeted therapy for ... - TI Pharma
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Chapter 4<br />
Figure 7. Inhibition of STAT3 and RIP1 blocks migration/invasion of TRAIL in A549 cells. (A) A549<br />
cells were incubated with or without chemical inhibitors of STAT3 (5,15‐DPP) or RIP1 (necrostatin‐1)<br />
and with or without TRAIL (50 ng/ml). Migration was determined after 8 h with the wound healing<br />
assay. Furthermore, invasion after 8 h (B) and cell <strong>death</strong> after 24 h (C) incubation were determined.<br />
Averages of three independent experiments (± s.d.) are shown. *p