towards improved death receptor targeted therapy for ... - TI Pharma
towards improved death receptor targeted therapy for ... - TI Pharma towards improved death receptor targeted therapy for ... - TI Pharma
TRAIL-induced kinases activation and apoptosis: towards improved death receptor targeted therapy for lung cancer Kaamar Azijli
The research in this thesis was performed within the framework of Dutch Top Institute Pharma, project T3‐112: “TNF‐ligands in cancer”. The experiments were performed at the Department of Medical Oncology, VU University Medical Center, Amsterdam, the Netherlands. Publication of this was financially supported by: Amgen, Roche Pharmaceuticals B.V., Bio‐Greiner B.V., Tebu‐Bio, Universitair Medisch Centrum Groningen, Rijksuniversiteit Groningen. Printed by: Ipskamp Drukkers ISBN: 978‐90‐367‐6110‐9 © Copyright: Kaamar Azijli, Amsterdam, 2013 All rights reserved. No part of this book may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronically, mechanically by photocopying, recording or otherwise without the written permission of the author
- Page 4 and 5: TRAIL‐induced kinases activation
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- Page 11 and 12: Chapter 1 GENERAL INTRODUCTION Canc
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- Page 15 and 16: Chapter 1 Reference List 1. Jemal A
- Page 17 and 18: Chapter 2 ABSTRACT Tumor necrosis f
- Page 19 and 20: Chapter 2 INTRODUCTION The death li
- Page 21 and 22: Chapter 2 In preclinical studies, a
- Page 23 and 24: Chapter 2 Table 1| Summary of the k
- Page 25 and 26: Chapter 2 proliferation could be pr
- Page 27 and 28: Chapter 2 Figure 2. Canonical and n
- Page 29 and 30: Chapter 2 associated with TRAIL res
- Page 31 and 32: Chapter 2 adhesion molecules [109].
- Page 33 and 34: Chapter 2 Reference List 1. Ashkena
- Page 35 and 36: Chapter 2 37. Tolcher AW, Mita M, M
- Page 37 and 38: Chapter 2 melanoma cells from TRAIL
- Page 39 and 40: Chapter 2 and ERK pathways. Circula
- Page 41 and 42: Chapter 3 ABSTRACT Tumor necrosis f
- Page 43 and 44: Chapter 3 inhibitors and TRAIL rece
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- Page 47 and 48: Chapter 3 P38 and JNK have opposing
- Page 49 and 50: Chapter 3 Figure 2 (continued). (e)
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TRAIL-induced kinases activation and<br />
apoptosis: <strong>towards</strong> <strong>improved</strong> <strong>death</strong><br />
<strong>receptor</strong> <strong>targeted</strong> <strong>therapy</strong> <strong>for</strong> lung cancer<br />
Kaamar Azijli
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