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Design of in vitro protein digestibility d h i l h i k assays ... - Europabio

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Digestibility and allergenicity risk assessment<br />

Digestibility g ystudies provide p useful data regard<strong>in</strong>g g gthe<br />

properties and characteristics <strong>of</strong> the novel prote<strong>in</strong> affect<strong>in</strong>g<br />

•Gut llum<strong>in</strong>al i lprocess<strong>in</strong>g i and d uptake k<br />

•Intracellular process<strong>in</strong>g and antigen presentation<br />

These may <strong>in</strong>fluence properties such as tolerance <strong>in</strong>duction<br />

or sensitisation <strong>in</strong> a host.<br />

They may also provide data on the stability and molecular<br />

mobility bili <strong>of</strong> f polypeptide l id cha<strong>in</strong>s hi<br />

MMutschlechner hl h et al l J Allergy All Cli Cl<strong>in</strong> IImmunoll2010 2010;125:711‐8<br />

125 711 8

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