EHRA EUROPACE 2013 - European Society of Cardiology
EHRA EUROPACE 2013 - European Society of Cardiology
EHRA EUROPACE 2013 - European Society of Cardiology
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WEdnEsdAy<br />
sEssiOns<br />
wednesday 26 June <strong>2013</strong> - morning<br />
08:30 - 10:00 Meet the Experts santorini<br />
From deciphering molecular pathogenesis to developing targeted new therapies<br />
Chairpersons: M. Anastasiou-nana (Athens, GR); s.C. dudley (Providence, Us)<br />
translational<br />
08:30 Genetics and molecular mechanisms <strong>of</strong> pathogenesis in cardiomyopathies and<br />
arrhythmias. 1326<br />
D. Sanoudou (Athens, GR)<br />
08:48 Ubiquitination and sUMOylation <strong>of</strong> ion channels. 1327<br />
H. Abriel (Bern, CH)<br />
09:06 imaging approaches in deciphering arrhythmogenesis. 1328<br />
M. Mongillo (Padova, IT)<br />
09:24 Identification and validation <strong>of</strong> novel therapeutic targets in arrhythmias. 1329<br />
S.E. Lehnart (Gottingen, DE)<br />
09:42 stem cells from bench side to fdA approval. 1330<br />
I. Terrovitis (Athens, GR)<br />
08:30 - 10:00 Main session Hydra<br />
Pathophysiological insights provided by EUTRAF: Progressive electrical<br />
uncoupling as determinant <strong>of</strong> AF chronification<br />
Chairpersons: A.J. Camm (london, Gb); s. Hatem (Paris, fR)<br />
basic science<br />
This session focuses on translational aspects <strong>of</strong> electrical uncoupling between muscle bundles providing<br />
the basis for conduction block and enhanced dissociation <strong>of</strong> electrical dissociation in the atria. Myocytefibroblast<br />
interactions have attracted a lot <strong>of</strong> attention in recent years as did the heterogeneity <strong>of</strong> the<br />
electrophysiological properties <strong>of</strong> atrial myocytes. This symposium will not only discuss the molecular<br />
mechanisms <strong>of</strong> altered fibroblast behavior and fibroblast-myocyte interactions but will also aim at<br />
translation <strong>of</strong> these findings to the organ-level and patients using non-invasive imaging techniques.<br />
08:30 Pr<strong>of</strong>ibrotic and prohypertrophic signalling in atrial fibrillation 1331<br />
A. Goette (Paderborn, DE)<br />
08:52 ROS signalling in atrial fibrillation 1332<br />
S.N. Reilly (Oxford, GB)<br />
09:15 Channel trafficking and cell-cell coupling in atrial fibrillation. 1333<br />
S. Hatem (Paris, FR)<br />
09:37 Towards a classification <strong>of</strong> atrial fibrillation based on the electrophysiological phenotype. 1334<br />
U. Schotten (Maastricht, NL)<br />
174
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