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As an innovation- and growth-oriented company, <strong>Bayer</strong> <strong>HealthCare</strong> also invests in<br />

setting up and maintaining collaborations with external partners. These partnerships<br />

cover a broad variety of models ranging from r&D collaborations, licensing and co-<br />

marketing agreements to regional alliances and acquisitions.<br />

Strategic alliances with international partners from academia are an important pillar of the<br />

company’s R&D strategy. Examples are the joint research center for innovative therapeutic<br />

approaches at Tsinghua University (China) and the collaboration with the<br />

German Cancer Research Center (Heidelberg). Other collaborations at earlier stage<br />

include the multi-target drug discovery alliance with Evotec AG from Germany in the<br />

area of endometriosis.<br />

With the targeted anticancer drug Nexavar (sorafenib), the Pharmaceuticals Division<br />

and Onyx Pharmaceuticals, Inc., USA, have gone all the way from drug discovery to<br />

market. Another example in the area of Oncology is the successful co-development of<br />

radium-223 dichloride with Algeta ASA from norway. <strong>Bayer</strong> <strong>HealthCare</strong> just recently<br />

submitted this substance for marketing authorization in the EU and the United States<br />

for the treatment of castration-resistant prostate cancer patients with bone metastases.<br />

In collaboration with Regeneron Pharmaceuticals, Inc., Eylea (aflibercept) has<br />

been successfully launched for the treatment of wet age-related macular degenera-<br />

tion and central retinal vein occlusion. Another example of a fruitful partnership is the<br />

co-development and co-promotion agreement with Janssen Pharmaceuticals for the<br />

anticoagulant Xarelto (rivaroxaban). This collaboration has led to launches in multiple<br />

locations worldwide.<br />

<strong>Bayer</strong> <strong>HealthCare</strong> Animal Health recently acquired the U.S. animal health business of<br />

Teva Pharmaceutical Industries. This transaction reinforces <strong>Bayer</strong>’s product offering in<br />

the USA with anti-infectives for livestock and adds reproductive hormones to the<br />

existing portfolio. The acquisition also strengthens the company’s companion animal<br />

franchise with the addition of dermatological, pet wellness and nutraceutical products.<br />

The Consumer Care Division continues to focus its business development efforts to<br />

strengthen its position in the United States and to accelerate growth in emerging<br />

markets including Brazil, China and Russia. In addition, the division will expand its<br />

portfolio into adjacent business categories, as well as Rx to OTC switch opportunities.<br />

BuSinESS DEvEloPMEnT<br />

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