New Entities in Smoking Related Lung Disease
New Entities in Smoking Related Lung Disease
New Entities in Smoking Related Lung Disease
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Pathology Recommendation 4/5<br />
• Comprehensive histologic subtyp<strong>in</strong>g used<br />
to assess patterns semiquantitatively <strong>in</strong><br />
5% <strong>in</strong>crements, choos<strong>in</strong>g a s<strong>in</strong>gle<br />
predom<strong>in</strong>ant pattern.<br />
• In multiple lung adenocarc<strong>in</strong>omas,<br />
comprehensive histologic subtyp<strong>in</strong>g may<br />
aid <strong>in</strong> determ<strong>in</strong><strong>in</strong>g whether tumors are<br />
metastases or separate primaries.<br />
Lesions larger than 3cm?<br />
• The data <strong>in</strong> the IASLC analysis were<br />
for tumors less than 2 or 3 cm.<br />
• If greater than 3 cm<br />
– “Lepidic predom<strong>in</strong>ant adenocarc<strong>in</strong>oma,<br />
suspect AIS or MIA.”<br />
– “Lepidic predom<strong>in</strong>ant adenocarc<strong>in</strong>oma.”<br />
Am J Surg Pathol. 2009 Dec;33(12):1752-64.<br />
5/28/2011<br />
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