Myelodysplastic Syndromes
Myelodysplastic Syndromes
Myelodysplastic Syndromes
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Neutrophil dysplasia<br />
• Hypo-, agranularity<br />
• Nuclear hypolobation<br />
(pseudo Pelger-Huet)<br />
• Irregular<br />
hypersegmentation<br />
• Pseudo Chediak-Higashi<br />
granules<br />
• Megaloblastic maturation<br />
• Small or large size<br />
• Auer rods (neoplastic!)<br />
Megakaryocytic dysplasia<br />
• Micromegakaryocytes<br />
• Nuclear hypolobation<br />
• Multinucleation (normal<br />
megs are uninuclear with<br />
lobation)<br />
5
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