Docteur de l'université Automatic Segmentation and Shape Analysis ...

Chapter 3
Hippocampal segmentation using multiple
atlases
׃םוּקָתּ םיִצֲעוֹי בֹרְבוּ דוֹס ןיֵאְבּ תוֹבשֲׁחַמ רֵפָה
Proverbs, 15:22.
The segmentation of hippocampus poses a challenge to the accurate and precise
assessment of hippocampal atrophy in AD. Multi-atlas based segmentation is one
successful approach to the automatic segmentation of hippocampus in structural
MR images. In this chapter, we first introduce the basic framework of multi-atlas
segmentation approach. Then, we develop a supervised method to construct a
population specific atlas set for the atlas-based segmentation. The problem of atlas
selection problem will also be discussed, to which we proposed two alternative atlas
selection strategy in addition to the commonly used selection by image similarity
ranking.
The results of population specific atlas construction have been published in “Super-
vised method to build an atlas database for multi-atlas segmentation-propagation,”
in SPIE Medical Imaging 2010: Computer-Aided Diagnosis. The results of the
alternative atlas selection strategies have been partially published in “Atlas selec-
tion strategy in multi-atlas segmentation propagation with locally weighted voting
using diversity-based MMR re-ranking,” in SPIE Medical Imaging 2011: Image
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