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Docteur de l'université Automatic Segmentation and Shape Analysis ...

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Chapter 2 Literature Review 33<br />

The triangulation of these l<strong>and</strong>marks forms a surface mesh of the anatomical object<br />

of interest. In general, the shape mo<strong>de</strong>ling by SSMs is based on this representation.<br />

In the context where the topology of the mesh is less relevant, shape information<br />

is a<strong>de</strong>quately <strong>de</strong>scribed by the l<strong>and</strong>mark representation, giving rise to the name<br />

‘Point Distribution Mo<strong>de</strong>l’ (PDM, Cootes et al., 1992), which covers the majority<br />

of current shape mo<strong>de</strong>ls (for survey, see Heimann <strong>and</strong> Meinzer, 2009).<br />

Apart from the representation by a set of l<strong>and</strong>marks, other approaches have been<br />

proposed in the literature of image registration, segmentation, <strong>and</strong> shape analysis.<br />

By taking advantage of the fact that most biological objects are homeomorphic<br />

to a sphere, one popular method for shape representation is the <strong>de</strong>composition of<br />

the l<strong>and</strong>mark coordinates into spherical harmonics (SPHARM, Brechbühler et al.,<br />

1995; Matheny <strong>and</strong> Goldgof, 1995), which are the eigen-functions for the angular<br />

part of the Laplacian operator. Wavelet technique on contour (Davatzikos et al.,<br />

2003) <strong>and</strong> sphere (Laga et al., 2006; Nain et al., 2007) has also been suggested<br />

for shape <strong>de</strong>scription. Medial representation (M-rep, Pizer et al., 1999, 2003;<br />

Yushkevich et al., 2003b) mo<strong>de</strong>ls geometry of the object by the skeleton of its<br />

medial locus with spokes normal to surface representing the boundary. Other<br />

representations inclu<strong>de</strong> spline based methods (Tsagaan et al., 2001, 2002), level<br />

set (Tsai et al., 2003; Pohl et al., 2006).<br />

2.2.2 Alignment of point sets<br />

For a given configuration of l<strong>and</strong>marks, its shape, or the size-<strong>and</strong>-shape, forms an<br />

equivalence class associated with a Eucli<strong>de</strong>an similarity, or rigid transformation<br />

group respectively. Without loss of generality, the shape or size-<strong>and</strong>-shape of the<br />

l<strong>and</strong>marks can be represented by one representative from its respective equivalence<br />

class. It may be translated to the origin <strong>and</strong> aligned to a specified orientation<br />

to preserve its size-<strong>and</strong>-shape, <strong>and</strong> scaled to a particular size for the analysis of<br />

its shape. Procrustes analysis <strong>and</strong> iterative closest point (ICP) are two major<br />

approaches to align the configuration point sets in shape analysis.

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