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Docteur de l'université Automatic Segmentation and Shape Analysis ...

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Chapter 2 Literature Review 29<br />

Wolz et al. (2009) <strong>and</strong> an EM approach is proposed to optimize the energy function<br />

(Lötjönen et al., 2010).<br />

2.1.3 Evaluation of segmentation<br />

The segmentation algorithms are usually evaluated in terms of their accuracy,<br />

volume,<br />

The accuracy of the segmentation can be measured by the overlap between the<br />

segmentation result <strong>and</strong> the ground truth. The Dice similarity coefficient (DSC,<br />

Dice, 1945), also known as the Kappa coefficient in some literature, indicates the<br />

percentage of the overlap between two segmentations<br />

DSC = 2|DS ∩ DR|<br />

, (2.1)<br />

|DS| + |DR|<br />

where DS is the segmented region, <strong>and</strong> DR is the reference region (e.g. manually<br />

segmented by experts, ground truth). Similar to DSC, the Jaccard in<strong>de</strong>x is also a<br />

measurement of the overlap, which is <strong>de</strong>fined as<br />

JI = |DS ∩ DR|<br />

. (2.2)<br />

|DS ∪ DR|<br />

If the voxels in the reference DR are regar<strong>de</strong>d as the actual positives, we can <strong>de</strong>fine<br />

the sensitivity<br />

<strong>and</strong> the specificity<br />

sensitivity = |DS ∩ DR|<br />

, (2.3)<br />

|DR|<br />

specificity = |DC S ∩ DC R|<br />

|DC , (2.4)<br />

R|<br />

where D C R corresponds to the voxels outsi<strong>de</strong> DR, i.e. the actual negative, <strong>and</strong> D C S<br />

corresponds to the voxels not labeled in DS.

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