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Docteur de l'université Automatic Segmentation and Shape Analysis ...

Docteur de l'université Automatic Segmentation and Shape Analysis ...

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Chapter 4 Statistical shape mo<strong>de</strong>l of Hippocampus 107<br />

4.4 Summary<br />

In this chapter, we <strong>de</strong>scribed the building of SSMs from the training shape data.<br />

The shape surfaces are first parameterized on a unit sphere by area-preserving<br />

mapping. The spherical parameterization of surfaces are then flattend to the<br />

shape image representation, which are re-parameterized to eliminate the spurious<br />

correspon<strong>de</strong>nces by groupwise optimization. The re-parameterization on the shape<br />

image is analogous to the non-rigid <strong>de</strong>formation in image registration, which is<br />

computed with fluid regularization. A fast algorithm solving fluid velocity using<br />

discrete sine transform is applied to regularize the shape reparameterization. The<br />

result SSM based on the correspon<strong>de</strong>nce in the parameter space is evaluated in<br />

terms of its compactness, generalization ability <strong>and</strong> specificity.<br />

Once the SSM is built, it is used to estimate the shape parameters of unseen<br />

surfaces or point sets. An EM algorithm is used to estimate the transformation<br />

<strong>and</strong> the <strong>de</strong>formation of the mo<strong>de</strong>l to fit the data with correspon<strong>de</strong>nce as the hid<strong>de</strong>n<br />

variable. The data term to be optimized is symmetric between the mo<strong>de</strong>l <strong>and</strong> the<br />

surface data in or<strong>de</strong>r to impose the consistency of the estimation. The SSM also<br />

provi<strong>de</strong> the shape prior for the MAP estimator which inclu<strong>de</strong>s a regularization<br />

term. The consistent symmetric estimation is shown to improve the <strong>de</strong>tails <strong>and</strong><br />

the precision of the reconstruction of the shape surface from the mo<strong>de</strong>l, <strong>and</strong> the<br />

shape prior regularization is necessary to avoid the problem of overfitting. With<br />

the presence of noises, mismatches, <strong>and</strong> disappearance of the correspon<strong>de</strong>nce, the<br />

regularized MAP gives more accurate estimation of shape parameters.

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