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Docteur de l'université Automatic Segmentation and Shape Analysis ...

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96 Chapter 4 Statistical shape mo<strong>de</strong>l of Hippocampus<br />

cost function can be rewritten as<br />

E = TA<br />

2kσ 2 ¯ X + Wb − T −1<br />

A (Yc) 2<br />

+ αTA<br />

2kY σ 2 Xc − T −1<br />

A (Y ) + BWb 2<br />

+ β<br />

2 bT Λ −1 b,<br />

(4.72)<br />

where TA is norm of the linear part of the affine transformation TA, which is the<br />

scaling factor of TA,<br />

Xc = B ∗ X, (4.73)<br />

<strong>and</strong> Λ is the diagonal matrix of eigenvalues {λm} of SSM. As opposed to B ∈<br />

R ky×k , B ∈ R 3kY ×3k is left multiplied to Wb ∈ R 3k , which is modified from B ∗<br />

⎛<br />

⎜ B<br />

⎜<br />

B = ⎜<br />

⎝<br />

∗ 11I3×3 B∗ 12I3×3 · · · B∗ B<br />

1kI3×3<br />

∗ 21I3×3 B∗ 22I3×3 · · · B∗ . .<br />

. ..<br />

2kI3×3<br />

.<br />

B∗ kY 1I3×3 B∗ kY 2I3×3 · · · B∗ ⎞<br />

⎟<br />

⎠<br />

kY kI3×3<br />

The minimum of the energy function is reached with the <strong>de</strong>rivative<br />

∂E<br />

∂b<br />

which is the solution to the linear system<br />

(4.74)<br />

= 0, (4.75)<br />

(<br />

1 α<br />

I + W<br />

k kY<br />

T B T<br />

BW σ<br />

+ 2β TA Λ−1<br />

)<br />

b = 1<br />

k WT (T −1<br />

A (Yc) − ¯ X)<br />

+ α<br />

W<br />

kY<br />

T B T −1<br />

(TA (Y ) − Xc).<br />

(4.76)<br />

To facilitate the computation of the term W T B T BW, sparsity on B can be im-<br />

posed by restricting the search of correspon<strong>de</strong>nce in (4.70) within a neighborhood<br />

of radius ρ.

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